{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:18:37Z","timestamp":1790115517320,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To prospectively investigate the incidence of symptoms and changes in the size of the apical bone destruction in symptom\u2010free root\u2010filled teeth with persistent apical periodontitis (AP) over 1\u2009year without treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>Patients referred to two specialist endodontic clinics in V\u00e4stra G\u00f6taland, Sweden, with asymptomatic periapical bone destructions (summing to \u2264\u200910\u2009mm in diameter, when measured in two dimensions) on intraoral radiographs were invited. After informed consent, participants underwent cone\u2010beam computed tomography (CBCT). Patients with bone destructions beyond cortical boundaries were excluded. A 1\u2010year follow\u2010up included recording subjective symptoms, clinical findings and estimating bone destruction size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 187 eligible patients, 171 (91.4%) participated. After CBCT, four were excluded, and 10 were lost to follow\u2010up. Among 157 patients, three developed symptomatic AP and were treated, and one tooth was lost due to fracture. Of the 153 patients with complete follow\u2010up, eight (5.2%) reported mild pain or discomfort but did not seek care. Lesion size changes were small (\n                      <jats:italic>M<\/jats:italic>\n                      \u2009=\u20090.059\u2009mm), with the mean increasing from 7.25\u2009mm (SD 2.11) to 7.31\u2009mm (SD 2.33), which was not statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings align with previous studies, suggesting that patients with symptom\u2010free root\u2010filled teeth with apical periodontitis rarely experience exacerbation or significant increase in size of bone destruction in the short term. Longer follow\u2010up is needed to identify potential risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.70059","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T15:23:06Z","timestamp":1763047386000},"page":"203-214","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Monitoring Asymptomatic Apical Periodontitis in Root\u2010Filled Teeth\u2014Results From a One\u2010Year Follow\u2010Up Prospective Study"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2835-5026","authenticated-orcid":false,"given":"M.","family":"Sayady\u2010\u00d6lander","sequence":"first","affiliation":[{"name":"Public Dental Service  V\u00e4stra G\u00f6talandsregionen Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0561-5431","authenticated-orcid":false,"given":"J.","family":"\u00d6stlin","sequence":"additional","affiliation":[{"name":"Public Dental Service  V\u00e4stra G\u00f6talandsregionen Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2546-9652","authenticated-orcid":false,"given":"V. 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