{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:12:57Z","timestamp":1790266377667,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:00:00Z","timestamp":1775865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:00:00Z","timestamp":1775865600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L222026"],"award-info":[{"award-number":["L222026"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62506013"],"award-info":[{"award-number":["62506013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To explore a deep learning (DL) model for determining the relationship between the maxillary sinus (MS) and maxillary posterior teeth (MPT) based on cone beam computed tomography (CBCT) images and measuring the distance automatically between the MS and MPT using a 3D point cloud algorithm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A CBCT dataset containing 88 maxillary sinuses (MSs) and 352 maxillary posterior teeth (MPT) was annotated, and the MS\u2010MPT distances were measured by clinicians as the ground truth. A segmentation model for MSs and MPT in CBCT images based on the U\u2010Net convolutional block attention (CBAM) architecture was trained and assessed using a 3\u2010fold cross\u2010validation strategy. Then, calibrated point clouds were reconstructed using segmented anatomical structure data, and the Euclidean distances between the MS and MPT were measured; the minimum distance was identified as the MS\u2010MPT distance. The performance of the model in terms of segmentation and distance measurement was evaluated, and the results were compared with the ground truth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Our segmentation model achieved a mean Dice similarity coefficient (DSC) of 0.959 and a mean Jaccard coefficient of 0.922 for MSs and a mean DSC of 0.913 and a mean Jaccard coefficient of 0.851 for MPT. The MS\u2010MPT distances determined by clinicians and the 3D point cloud method demonstrated strong consistency (\n                      <jats:italic>\u03d2<\/jats:italic>\n                      \u2009&gt;\u20090.993,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). In terms of the model and clinicians, the mean negative signed error was 0.63\u2009mm (95% CI, 0.59\u20130.66\u2009mm), and the successful detection rate (SDR) for the root apex of MPT reached 70.3% at the 1\u2009mm threshold.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study, an automated framework that combines deep learning\u2010driven segmentation and three\u2010dimensional point cloud analysis was developed to quantify the relationship between the maxillary sinus and maxillary posterior teeth and achieved reliable detection accuracy across diverse anatomical variations in CBCT scans.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.70141","type":"journal-article","created":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:05:59Z","timestamp":1775891159000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Deep\u2010Learning\u2010Based Automatic Measurement of the Distance Between the Maxillary Sinus and Maxillary Posterior Teeth on\n                    <scp>CBCT<\/scp>\n                    Images"],"prefix":"10.1111","author":[{"given":"Cheng\u2010Ye","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cariology and Endodontology Peking University School and Hospital of Stomatology  Beijing China"},{"name":"National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials  Beijing China"},{"name":"Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Ming","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cariology and Endodontology Peking University School and Hospital of Stomatology  Beijing China"},{"name":"National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials  Beijing China"},{"name":"Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke\u2010Xin","family":"Yi","sequence":"additional","affiliation":[{"name":"School of Computer Science Peking University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen\u2010Bing","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Computer Science Peking University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Software and Microelectronics Peking University &amp; National Engineering Research Center for Software Engineering, Peking University &amp; Key Laboratory of High Confidence Software Technologies (Peking University), Ministry of Education  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Yan","sequence":"additional","affiliation":[{"name":"School of Computer Science Peking University  Beijing China"},{"name":"School of Software and Microelectronics Peking University &amp; National Engineering Research Center for Software Engineering, Peking University &amp; Key Laboratory of High Confidence Software Technologies (Peking University), Ministry of Education  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Hong","family":"Liang","sequence":"additional","affiliation":[{"name":"National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials  Beijing China"},{"name":"Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials  Beijing China"},{"name":"Department of Oral Emergency Peking University School and Hospital of Stomatology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,11]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Head & Neck Surgery\u2014Otolaryngology","author":"Bailey B. J.","year":"2006"},{"issue":"1","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/s12903-023-02881-8","article-title":"Evaluating the Accuracy of Automated Cephalometric Analysis Based on Artificial Intelligence","volume":"23","author":"Bao H.","year":"2023","journal-title":"BMC Oral Health"},{"issue":"4","key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s00784-011-0620-1","article-title":"Correlation of Cone Beam Computed Tomography (CBCT) Findings in the Maxillary Sinus With Dental Diagnoses: A Retrospective Cross\u2010Sectional Study","volume":"16","author":"Br\u00fcllmann D. D.","year":"2012","journal-title":"Clinical Oral Investigations"},{"issue":"5","key":"e_1_2_12_5_1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1159\/000527418","article-title":"Detection of Proximal Caries Lesions on Bitewing Radiographs Using Deep Learning Method","volume":"56","author":"Chen X.","year":"2022","journal-title":"Caries Research"},{"issue":"1","key":"e_1_2_12_6_1","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-18436-w","article-title":"Deep Learning\u2010Based Fully Automatic Segmentation of the Maxillary Sinus on Cone\u2010Beam Computed Tomographic Images","volume":"12","author":"Choi H.","year":"2022","journal-title":"Scientific Reports"},{"issue":"1","key":"e_1_2_12_7_1","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-29637-2","article-title":"A Fully Automatic AI System for Tooth and Alveolar Bone Segmentation From Cone\u2010Beam CT Images","volume":"13","author":"Cui Z.","year":"2022","journal-title":"Nature Communications"},{"issue":"10","key":"e_1_2_12_8_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e31052","article-title":"AI Model to Detect Contact Relationship Between Maxillary Sinus and Posterior Teeth","volume":"10","author":"Ding W.","year":"2024","journal-title":"Heliyon"},{"issue":"1","key":"e_1_2_12_9_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/0103-6440201600679","article-title":"Study of Anatomical Relationship Between Posterior Teeth and Maxillary Sinus Floor in a Subpopulation of the Brazilian Central Region Using Cone\u2010Beam Computed Tomography\u2014Part 2","volume":"27","author":"Estrela C.","year":"2016","journal-title":"Brazilian Dental Journal"},{"issue":"3","key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0901-5027(99)80136-2","article-title":"Complications After Apicoectomy in Maxillary Premolar and Molar Teeth","volume":"28","author":"Freedman A.","year":"1999","journal-title":"International Journal of Oral and Maxillofacial Surgery"},{"issue":"12","key":"e_1_2_12_11_1","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1902\/jop.2006.060197","article-title":"The Mental Foramen and Nerve: Clinical and Anatomical Factors Related to Dental Implant Placement: A Literature Review","volume":"77","author":"Greenstein G.","year":"2006","journal-title":"Journal of Periodontology"},{"issue":"1","key":"e_1_2_12_12_1","doi-asserted-by":"crossref","DOI":"10.3390\/jcm13010197","article-title":"Evaluating a Periapical Lesion Detection CNN on a Clinically Representative CBCT Dataset\u2010A Validation Study","volume":"13","author":"Hadzic A.","year":"2023","journal-title":"Journal of Clinical Medicine"},{"issue":"1","key":"e_1_2_12_13_1","doi-asserted-by":"crossref","DOI":"10.1007\/s00784-025-06191-x","article-title":"A Platform Combining Automatic Segmentation and Automatic Measurement of the Maxillary Sinus and Adjacent Structures","volume":"29","author":"He J.","year":"2025","journal-title":"Clinical Oral Investigations"},{"issue":"1","key":"e_1_2_12_14_1","doi-asserted-by":"crossref","DOI":"10.1186\/s12903-024-05396-y","article-title":"Proximity of Maxillary Molar Palatal Roots to Adjacent Structures for Endodontic Microsurgery: A Cone\u2010Beam Computed Tomography Study","volume":"25","author":"Huang X.","year":"2025","journal-title":"BMC Oral Health"},{"key":"e_1_2_12_15_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.104120","article-title":"Clinical Actionability of Triaging DNA Mismatch Repair Deficient Colorectal Cancer From Biopsy Samples Using Deep Learning","volume":"81","author":"Jiang W.","year":"2022","journal-title":"eBioMedicine"},{"issue":"4","key":"e_1_2_12_16_1","article-title":"Deep Active Learning for Automatic Segmentation of Maxillary Sinus Lesions Using a Convolutional Neural Network","volume":"11","author":"Jung S.\u2010K.","year":"2021","journal-title":"Diagnostics (Basel, Switzerland)"},{"issue":"4","key":"e_1_2_12_17_1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1055\/s-0039-1697866","article-title":"An Assessment of the Relationship Between the Maxillary Sinus Floor and the Maxillary Posterior Teeth Root Tips Using Dental Cone\u2010Beam Computerized Tomography","volume":"4","author":"Kilic C.","year":"2010","journal-title":"European Journal of Dentistry"},{"issue":"1","key":"e_1_2_12_18_1","doi-asserted-by":"crossref","DOI":"10.1038\/s41368-024-00294-z","article-title":"Fully Automatic AI Segmentation of Oral Surgery\u2010Related Tissues Based on Cone Beam Computed Tomography Images","volume":"16","author":"Liu Y.","year":"2024","journal-title":"International Journal of Oral Science"},{"key":"e_1_2_12_19_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.neunet.2024.106765","article-title":"Analog Spiking U\u2010Net Integrating CBAM&ViT for Medical Image Segmentation","volume":"181","author":"Ma Y.","year":"2025","journal-title":"Neural Networks: The Official Journal of the International Neural Network Society"},{"issue":"3","key":"e_1_2_12_20_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s11882-009-0035-0","article-title":"Maxillary Sinusitis of Odontogenic Origin","volume":"9","author":"Mehra P.","year":"2009","journal-title":"Current Allergy and Asthma Reports"},{"key":"e_1_2_12_21_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/iej.70033","article-title":"Prevalence and Predisposing Factors of Periapical Osteoperiostitis: A Retrospective Cross\u2010Sectional Study","volume":"59","author":"Mora M.","year":"2025","journal-title":"International Endodontic Journal"},{"issue":"1","key":"e_1_2_12_22_1","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-11483-3","article-title":"Convolutional Neural Network for Automatic Maxillary Sinus Segmentation on Cone\u2010Beam Computed Tomographic Images","volume":"12","author":"Morgan N.","year":"2022","journal-title":"Scientific Reports"},{"issue":"8","key":"e_1_2_12_23_1","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1111\/iej.13115","article-title":"Cone Beam Computed Tomography in Endodontics \u2010 a Review of the Literature","volume":"52","author":"Patel S.","year":"2019","journal-title":"International Endodontic Journal"},{"issue":"24","key":"e_1_2_12_24_1","doi-asserted-by":"crossref","first-page":"245009","DOI":"10.1088\/1361-6560\/ad953f","article-title":"Tooth Point Cloud Resampling Method Based on Divergence Index and Improved Euclidean Clustering Rule","volume":"69","author":"Qiu Z.","year":"2024","journal-title":"Physics in Medicine & Biology"},{"issue":"1","key":"e_1_2_12_25_1","first-page":"e38","article-title":"Accidental Displacement of Dental Implants Into the Maxillary Sinus: A Report of Nine Cases","volume":"11","author":"Ridaura\u2010Ruiz L.","year":"2009","journal-title":"Clinical Implant Dentistry and Related Research"},{"key":"e_1_2_12_26_1","first-page":"234","volume-title":"International Conference on Medical Image Computing and Computer\u2010Assisted Intervention","author":"Ronneberger O.","year":"2015"},{"issue":"5","key":"e_1_2_12_27_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.bjoms.2006.10.013","article-title":"Incidence and Predictive Factors for Perforation of the Maxillary Antrum in Operations to Remove Upper Wisdom Teeth: Prospective Multicentre Study","volume":"45","author":"Rothamel D.","year":"2007","journal-title":"British Journal of Oral & Maxillofacial Surgery"},{"key":"e_1_2_12_28_1","article-title":"VM\u2010UNet: Vision Mamba UNet for Medical Image Segmentation","author":"Ruan J.","year":"2024","journal-title":"arXiv"},{"issue":"3","key":"e_1_2_12_29_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.tripleo.2005.09.031","article-title":"Correlation Between Maxillary Sinus Floor Topography and Related Root Position of Posterior Teeth Using Panoramic and Cross\u2010Sectional Computed Tomography Imaging","volume":"102","author":"Sharan A.","year":"2006","journal-title":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},{"key":"e_1_2_12_30_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.imavis.2023.104890","article-title":"Feature Extraction and Representation Learning of 3D Point Cloud Data","volume":"142","author":"Si H.","year":"2024","journal-title":"Image and Vision Computing"},{"issue":"16","key":"e_1_2_12_31_1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/clr.13346","article-title":"The Accuracy of Static Computer\u2010Aided Implant Surgery: A Systematic Review and Meta\u2010Analysis","volume":"29","author":"Tahmaseb A.","year":"2018","journal-title":"Clinical Oral Implants Research"},{"issue":"8","key":"e_1_2_12_32_1","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.jcms.2015.07.021","article-title":"Etiology and Clinical Characteristics of Symptomatic Unilateral Maxillary Sinusitis: A Review of 174 Cases","volume":"43","author":"Troeltzsch M.","year":"2015","journal-title":"Journal of Cranio\u2010Maxillofacial Surgery"},{"issue":"8","key":"e_1_2_12_33_1","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.3390\/s21082587","article-title":"3D Face Point Cloud Reconstruction and Recognition Using Depth Sensor","volume":"21","author":"Wang C. W.","year":"2021","journal-title":"Sensors"},{"key":"e_1_2_12_34_1","first-page":"3","volume-title":"Proceedings of the European Conference on Computer Vision (ECCV)","author":"Woo S.","year":"2018"},{"key":"e_1_2_12_35_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.media.2025.103547","article-title":"Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation","volume":"102","author":"Wu J.","year":"2025","journal-title":"Medical Image Analysis"},{"issue":"9","key":"e_1_2_12_36_1","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1007\/s11548-020-02228-6","article-title":"Automatic CT Image Segmentation of Maxillary Sinus Based on VGG Network and Improved V\u2010Net","volume":"15","author":"Xu J.","year":"2020","journal-title":"International Journal of Computer Assisted Radiology and Surgery"},{"issue":"6","key":"e_1_2_12_37_1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/ID.0b013e31827464fc","article-title":"Topographic Analysis of Maxillary Premolars and Molars and Maxillary Sinus Using Cone Beam Computed Tomography","volume":"21","author":"Yoshimine S.\u2010I.","year":"2012","journal-title":"Implant Dentistry"},{"issue":"3","key":"e_1_2_12_38_1","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.neuroimage.2006.01.015","article-title":"User\u2010Guided 3D Active Contour Segmentation of Anatomical Structures: Significantly Improved Efficiency and Reliability","volume":"31","author":"Yushkevich P. A.","year":"2006","journal-title":"NeuroImage"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.70141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iej.70141","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.70141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:06:05Z","timestamp":1775891165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iej.70141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,11]]},"references-count":37,"alternative-id":["10.1111\/iej.70141"],"URL":"https:\/\/doi.org\/10.1111\/iej.70141","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"value":"0143-2885","type":"print"},{"value":"1365-2591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,11]]},"assertion":[{"value":"2025-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"iej.70141"}}