{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:44:03Z","timestamp":1792176243121,"version":"4.4.0"},"reference-count":56,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To correlate the outcome of partial pulpotomy (PP) with the time taken to arrest pulpal bleeding in cariously\u2010exposed mature permanent teeth with a clinical diagnosis of symptomatic irreversible pulpitis (SIP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>\n                      This single centre, one\u2010arm clinical trial was registered in the Clinical Trials Registry\u2014India (CTRI\/2023\/06\/054485). One\u2010hundred and thirty\u2010five permanent molar teeth with extremely deep caries presenting with a clinical diagnosis of SIP were recruited. PP was performed following a standardized protocol, by first amputating 2\u20133\u2009mm of exposed coronal pulp, prior to haemostasis being achieved using 2.5% sodium hypochlorite with pressure up to 15\u2009min. The time taken to arrest bleeding was recorded and categorized into three groups: 1\u20135\u2009min, 6\u201310\u2009min and 11\u201315\u2009min. Biodentine was used as the pulp capping material and the tooth restored. Pain scores were recorded pre\u2010operatively, at 24\u2009h, 48\u2009h and 7\u2009days post\u2010operatively using a visual analogue scale (VAS). Clinical and radiographic evaluations were carried out at 6 and 12 months. Statistical analysis included: Friedman test, Kruskal\u2010Wallis,\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, Mann Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test, Cramer's\n                      <jats:italic>V<\/jats:italic>\n                      coefficient (\n                      <jats:italic>V<\/jats:italic>\n                      ) and Spearman correlation (rho). The significance level was\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 135 cases, 123 cases were evaluated at 12\u2010months reflecting a recall rate of 91.1% (123\/135). The overall success rate of PP at 12\u2009months was 91.9%. No statistically significant association was shown between the treatment outcome and time taken to achieve haemostasis across the three categories. However, a weak correlation was demonstrated between bleeding time and pre\u2010operative pain intensity (rho\u2009=\u20090.262;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). A moderate association was evident between patient age and treatment outcome (\n                      <jats:italic>V<\/jats:italic>\n                      \u2009=\u20090.38;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Other variables, such as gender, tooth type, site of caries, pre\u2010operative VAS score, pain on percussion and periapical index score did not significantly influence the outcome (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within the limitations of this study, time required to achieve pulpal haemostasis (up to 15\u2009min) did not significantly influence treatment outcome at 12\u2009months, indicating that haemostasis time may not be a reliable predictor of success. PP demonstrated a high overall success rate, suggesting that favourable outcomes can be achieved even in cases with prolonged bleeding, provided adequate haemostasis is attained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The study was registered prospectively with the Clinical Trials Registry of India with Registration No. (CTRI\/2023\/06\/054485)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.70214","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:42:12Z","timestamp":1782978132000},"page":"2358-2371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Pulpal Haemostasis Time on Partial Pulpotomy Outcome in Cariously Exposed Mature Permanent Teeth With Symptomatic Irreversible Pulpitis"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4982-2438","authenticated-orcid":false,"given":"Saada","family":"Sulaiman","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7264-8506","authenticated-orcid":false,"given":"Ruchika Roongta","family":"Nawal","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5656-4628","authenticated-orcid":false,"given":"Sudha","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6805-4695","authenticated-orcid":false,"given":"Sangeeta","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6711-4665","authenticated-orcid":false,"given":"Seema","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry Fergus","family":"Duncan","sequence":"additional","affiliation":[{"name":"Division of Restorative Dentistry Trinity College Dublin, Dublin Dental University Hospital  Dublin 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