{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:21:08Z","timestamp":1787980868639,"version":"build-2784847793"},"reference-count":52,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This multicenter cross\u2010sectional study evaluated the prevalence and variables statistically associated with primary and post\u2010treatment apical periodontitis (AP) in subjects from eight Hispanic American countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>Digital panoramic radiographs from subjects living in Argentina, Colombia, Ecuador, Guatemala, Mexico, Dominican Republic, Uruguay and Venezuela were analyzed. Teeth were evaluated for diverse factors, including the periapical status and presence of root canal treatment, caries, coronal restoration, intraradicular post, root resorption and periodontal involvement. Quality of root canal treatment and coronal restorations was also recorded. Associations between these diverse variables and AP were evaluated using chi\u2010square tests and multivariable mixed\u2010effects logistic regression with a random intercept for patient to account for within\u2010patient clustering of teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 11\u2009850 subjects (294\u2009662 teeth) were included; 51.5% of the subjects and 5.5% of the examined teeth had AP. Ecuador (62%) and Argentina (61%) had the highest AP prevalence per subject, whereas Mexico had the lowest (37%). Intermediate values were observed in Venezuela (57%), Guatemala (57%), Colombia (47%), Dominican Republic (46%) and Uruguay (45%). In general, 43% of the subjects had at least one root canal\u2013treated tooth. Primary and post\u2010treatment AP were observed in 3% and 42% of the teeth, respectively. Of the teeth with primary AP, 51% showed coronal restorations, and 32% had caries. Post\u2010treatment AP was significantly associated with inadequate root canal fillings, inadequate coronal restorations and inadequate intraradicular posts (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of AP in the Hispanic American countries evaluated was high, affecting nearly half of the population. Post\u2010treatment AP was highly prevalent and predominantly linked to inadequate root canal fillings, deficient or absent coronal restorations and intraradicular posts. These findings emphasize the importance of strengthening caries prevention strategies and improving the quality of endodontic and restorative care to reduce the burden of apical periodontitis in these regions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.70254","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T06:50:16Z","timestamp":1786431016000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Apical Periodontitis in Eight Hispanic American Countries"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1702-0919","authenticated-orcid":false,"given":"Sandra R.","family":"Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Member of the Endochat Research Group  Rio de Janeiro Brazil"},{"name":"Department of Endodontics and Research, Faculty of Dentistry Universidad Francisco Marroqu\u00edn  Guatemala City 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Dentistry, Endodontics Division, Faculty of Dentistry Universidad de la Rep\u00fablica  Montevideo Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Rend\u00f3n","sequence":"additional","affiliation":[{"name":"Member of the Endochat Research Group  Rio de Janeiro Brazil"},{"name":"Periodontics, Health, and Education Research Group, Faculty of Dentistry Universidad de Antioquia  Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0736-298X","authenticated-orcid":false,"given":"Gabriela","family":"Martin","sequence":"additional","affiliation":[{"name":"Member of the Endochat Research Group  Rio de Janeiro Brazil"},{"name":"Posgraduate Program in Endodontics, Faculty of Health Sciences Universidad Cat\u00f3lica de C\u00f3rdoba  C\u00f3rdoba 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