{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T05:27:52Z","timestamp":1786512472752,"version":"build-2736575974"},"reference-count":102,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Root canal therapy (RCT) is the primary treatment modality for pulpal and periapical diseases. Although the fundamental objective of RCT has remained unchanged for over a century, its technical details have been continuously refined and transformed. Preoperative diagnostic approaches have evolved from two\u2010dimensional imaging to three\u2010dimensional volumetric reconstructions and, more recently, to artificial intelligence\u2010assisted analytical frameworks. Treatment modalities have progressed from manual instrumentation to motor\u2010driven systems and guided or robotic\u2010assisted interventions. Disinfection strategies have also begun to shift from passive chemical irrigation towards actively guided nano\u2010enabled systems. Moreover, obturation materials have advanced from inert substances to bioactive compounds and, prospectively, to adaptive trends. These transitions reflect not only technological progress but also the continuing efforts of endodontists to improve precision, safety, efficiency, and biological outcomes. However, the primary goal of RCT remains the effective elimination of infection and the prevention of reinfection. In this review, the term \u2018Smart RCT\u2019 is used as a conceptual framework that integrates digital intelligence, engineering\u2010based operative assistance, and material\u2010based biological functions. We systematically synthesise contemporary evidence on the development and application of smart technologies across the major stages of RCT. By critically evaluating both the potential and current limitations of these technologies, this review aims to provide an evidence\u2010based perspective on the integration of intelligent advances into contemporary endodontic decision\u2010making and clinical practice.<\/jats:p>","DOI":"10.1111\/iej.70256","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T04:39:46Z","timestamp":1786509586000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Smart Root Canal Therapy: Intelligence Refinement of Clinical Procedures"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1035-9802","authenticated-orcid":false,"given":"Yu","family":"Du","sequence":"first","affiliation":[{"name":"Hospital of Stomatology, Guanghua School of Stomatology Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Stomatology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tian","sequence":"additional","affiliation":[{"name":"Hospital of Stomatology, Guanghua School of Stomatology Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Stomatology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5367-1308","authenticated-orcid":false,"given":"Maobin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Endodontology Temple University Kornberg School of Dentistry  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5749-2910","authenticated-orcid":false,"given":"Xi","family":"Wei","sequence":"additional","affiliation":[{"name":"Hospital of Stomatology, Guanghua School of Stomatology Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Stomatology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"issue":"5","key":"e_1_2_15_2_1","doi-asserted-by":"crossref","DOI":"10.3390\/jfb15050134","article-title":"Comparative Analysis of Interfacial Adaptation and Depth Penetration of Recent Hiflow Versus Regular Bioceramic Sealers in Conjunction With Bc Gutta\u2010Percha Points Using Two Different Obturation Techniques\u2010a Preliminary Report of an Ex\u00a0Vivo Study","volume":"15","author":"Abu\u2010Zeid S. 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