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The purpose of this study was to examine the effect of obesity and resistance training, considered separately or in association, on testicular function and reproductive capacity. Twenty pubertal male Wistar rats were distributed into four groups: control (C) and exercise (E) groups that received standard rat chow; and obese (O) and obese with exercise (<jats:styled-content style=\"fixed-case\">OE<\/jats:styled-content>) groups that received a high\u2010fat diet. All the groups received filtered water during the experimental conditions. Groups E and <jats:styled-content style=\"fixed-case\">OE<\/jats:styled-content> were submitted to 8 weeks of high\u2010intensity intermittent training. Afterwards, testes were collected for sperm count, spermatogenic kinetics, histopathology, morphometry and immunodetection of androgen receptors (<jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content>). The vas deferens was collected for sperm morphology. The results showed that obesity increased body weight, naso\u2010anal length, liver and epididymal fat weight, abnormal spermatozoa and immunodetectable AR. Intermittent exercise decreased daily sperm production (<jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content>), sperm count and normal spermatozoa, whereas the number of tubules with immunodetectable <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content> increased. The combination of obesity and intermittent training led to reduced sperm count and <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content>, although abnormal spermatozoa and the number of tubules with immunodetectable <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content> increased. Thus, in conclusion, both obesity and resistance training impaired testicular function during puberty in rats; and this type of exercise has also been shown to be detrimental to testicular physiology.<\/jats:p>","DOI":"10.1111\/iep.12270","type":"journal-article","created":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T09:09:05Z","timestamp":1526893745000},"page":"95-102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Intermittent resistance exercise and obesity, considered separately or combined, impair spermatic parameters in adult male Wistar rats"],"prefix":"10.1111","volume":"99","author":[{"given":"Ana Paula Franco","family":"Punhagui","sequence":"first","affiliation":[{"name":"General Biology Department Biological Sciences Center State University of Londrina\u2014UEL Londrina Brazil"},{"name":"General Pathology Department Biological Sciences Center State University of Londrina\u2014UEL Londrina 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