{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T11:14:45Z","timestamp":1781781285746,"version":"3.54.5"},"reference-count":35,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["international-journal-of-gynecological-cancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Gynecological Cancer"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1111\/igc.0b013e3181acae33","type":"journal-article","created":{"date-parts":[[2010,12,3]],"date-time":"2010-12-03T13:36:56Z","timestamp":1291383416000},"page":"1131-1136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Primary Vulvar Ewing Sarcoma\/Primitive Neuroectodermal Tumor"],"prefix":"10.1016","volume":"19","author":[{"given":"Handan","family":"Cetiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gozde","family":"Kir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward P.","family":"Gelmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metin","family":"Ozdemirli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/IGC.0b013e3181acae33_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000478-199301000-00001","article-title":"Primitive neuroectodermal tumor and Ewing\u2019s sarcoma","volume":"17","author":"Dehner","year":"1993","journal-title":"Am JSurg Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0010","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1002\/1097-0142(19910401)67:7<1886::AID-CNCR2820670712>3.0.CO;2-U","article-title":"MIC2 is a specific marker for Ewing\u2019s sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing\u2019s sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration","volume":"67","author":"Ambros","year":"1991","journal-title":"Cancer."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0015","first-page":"1294","article-title":"Detection of the (11;22)(q24;q12) translocation of Ewing\u2019s sarcoma and peripheral neuroectodermal tumor by reverse transcription polymerase chain reaction","volume":"143","author":"Downing","year":"1993","journal-title":"Am JPathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0020","first-page":"141","article-title":"EWS rearrangement in Ewing\u2019s sarcoma and peripheral neuroectodermal tumor. Molecular detection and correlation with cytogenetic analysis and MIC2 expression","volume":"2","author":"Ladanyi","year":"1993","journal-title":"Diagn Mol Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0025","first-page":"408","article-title":"Immunostaining of the p30\/32MIC2 antigen and molecular detection of EWS for the diagnosis of Ewing\u2019s sarcoma and peripheral neuroectodermal tumor","volume":"27","author":"Scotlandi","year":"1996","journal-title":"HumPathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0030","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.anndiagpath.2006.12.019","article-title":"Superficial primitive neuroectodermal tumor\/Ewing sarcoma (PN\/ES): same tumor as deep PN\/ES or new entity?","volume":"11","author":"Ehrig","year":"2007","journal-title":"Ann Diagn Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0035","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1046\/j.1365-2559.1997.2770865.x","article-title":"Clinicopathological characteristics of peripheral primitive neuroectodermal tumour of skin and subcutaneous tissue","volume":"31","author":"Banerjee","year":"1997","journal-title":"Histopathology."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0040","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0360-3016(99)00391-0","article-title":"Cutaneous and subcutaneous Ewing\u2019s sarcoma: an indolent disease","volume":"46","author":"Chow","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0045","first-page":"158","article-title":"Rare lesion of the vulva","volume":"40","author":"Habib","year":"1992","journal-title":"Arch Anat Cytol Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0050","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1006\/gyno.1994.1204","article-title":"Peripheral primitive neuroectodermal tumor of the vulva","volume":"54","author":"Scherr","year":"1994","journal-title":"Gynecol Oncol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0055","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/00004347-199501000-00010","article-title":"Primary vulvar sarcomas","volume":"14","author":"Nirenberg","year":"1995","journal-title":"Int J Gynecol Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0060","first-page":"161","article-title":"A peripheral neuroectodermal tumor of the vulva","volume":"8","author":"Paredes","year":"1995","journal-title":"Acta Med Port."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0065","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/00004347-200004000-00002","article-title":"Primary vulvar and vaginal extraosseous Ewing\u2019s sarcoma\/peripheral neuroectodermal tumor: diagnostic confirmation with CD99 immunostaining and reverse transcriptase-polymerase chain reaction","volume":"19","author":"Vang","year":"2000","journal-title":"Int J Gynecol Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0070","first-page":"832","article-title":"Extraosseous Ewing sarcoma of the vagina","volume":"96","author":"Farley","year":"2000","journal-title":"Obstet Gynecol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0075","first-page":"263","article-title":"Primary uterine and vulvar Ewing\u2019s sarcoma\/peripheral neuroectodermal tumors in children: two unusual locations","volume":"21","author":"Lazure","year":"2001","journal-title":"Ann Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0080","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1159\/000328353","article-title":"Peripheral primitive neuroectodermal tumor of the vulva: report of a case with imprint cytology","volume":"45","author":"Takeshima","year":"2001","journal-title":"Acta Cytol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0085","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/030089160208800419","article-title":"The first report of extraosseous Ewing\u2019s sarcoma in the rectovaginal septum","volume":"88","author":"Petkovic","year":"2002","journal-title":"Tumori."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0090","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S0090-8258(03)00500-6","article-title":"Primitive neuroectodermal tumor of the vagina","volume":"91","author":"Gaona-Luviano","year":"2003","journal-title":"Gynecol Oncol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0095","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.ygyno.2003.10.051","article-title":"Primary Ewing\u2019s sarcoma-primitive neuroectodermal tumor of the vagina","volume":"92","author":"Liao","year":"2004","journal-title":"Gynecol Oncol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0100","first-page":"1177","article-title":"Ewing\u2019s sarcoma of the vulva\u2014a case report","volume":"15","author":"Moodley","year":"2005","journal-title":"Int J Gynecol Cancer."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0105","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1136\/jcp.2006.040931","article-title":"Ewing family of tumours involving the vulva and vagina: report of a series of four cases","volume":"60","author":"McCluggage","year":"2007","journal-title":"J Clin Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0110","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1080\/15513819609168678","article-title":"EWS\/FLI-1 fusion transcript detection and MIC2 immunohistochemical staining in the diagnosis of Ewing\u2019s sarcoma","volume":"16","author":"Lee","year":"1996","journal-title":"Pediatr Pathol Lab Med."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/modpathol.3800486","article-title":"Molecular diagnosis of Ewing sarcoma\/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumors","volume":"19","author":"Bridge","year":"2006","journal-title":"Mod Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0120","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1056\/NEJMoa020890","article-title":"Addition of ifosfamide and etoposide to standard chemotherapy for Ewing\u2019s sarcoma and primitive neuroectodermal tumor ofbone","volume":"348","author":"Grier","year":"2003","journal-title":"NEngl JMed."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0125","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1200\/JCO.1997.15.2.583","article-title":"Detection of circulating tumor cells in patients with Ewing\u2019s sarcoma and peripheral primitive neuroectodermal tumor","volume":"15","author":"West","year":"1997","journal-title":"J Clin Oncol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0130","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0165-4608(86)90001-4","article-title":"Cytogenetic characterization of selected small round cell tumors of childhood","volume":"21","author":"Whang-Peng","year":"1986","journal-title":"Cancer Genet Cytogenet."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0135","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0165-4608(88)90285-3","article-title":"Chromosomes in Ewing\u2019s sarcoma. I. An evaluation of 85 cases of remarkable consistency of t(11;22)(q24;q12)","volume":"32","author":"Turc-Carel","year":"1988","journal-title":"Cancer Genet Cytogenet."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0140","first-page":"507","article-title":"Experimental evidence for a neural origin of Ewing\u2019s sarcoma of bone","volume":"127","author":"Cavazzana","year":"1987","journal-title":"Am JPathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0145","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1038\/bjc.1991.458","article-title":"Evidence for heterogeneous groups of neuronal differentiation of Ewing\u2019s sarcoma","volume":"64","author":"Hara","year":"1991","journal-title":"Br J Cancer."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0150","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1001\/archsurg.138.3.281","article-title":"Adult soft tissue Ewing sarcoma or primitive neuroectodermal tumors: predictors of survival?","volume":"138","author":"Martin","year":"2003","journal-title":"Arch Surg."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0155","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/modpathol.3880455","article-title":"Differentiating lymphoblastic lymphoma and Ewing\u2019s sarcoma: Lymphocyte markers and gene rearrangement","volume":"14","author":"Ozdemirli","year":"2001","journal-title":"Mod Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0160","first-page":"486^94","article-title":"Immunohistochemical profile of monoclonal antibody O13: antibody that recognizes glycoprotein p30\/32MIC2 and is useful in diagnosing Ewing\u2019s sarcoma and peripheral neuroepithelioma","volume":"18","author":"Weidner","year":"1994","journal-title":"Am JSurg Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0165","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/00019606-199606000-00005","article-title":"Detection of t(11;22)(q24;q12) translocation breakpoint in paraffin-embedded tissue of the Ewing\u2019s sarcoma family by nested reverse transcription-polymerase chain reaction","volume":"5","author":"Adams","year":"1996","journal-title":"Diagn Mol Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0170","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0046-8177(99)90012-6","article-title":"Detection of EWS-FLI-1 fusion in Ewing\u2019s sarcoma\/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffin-embedded tissue","volume":"30","author":"Kumar","year":"1999","journal-title":"Hum Pathol."},{"key":"10.1111\/IGC.0b013e3181acae33_bb0175","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/01.pdm.0000140192.27878.97","article-title":"Molecular diagnosis of Ewing\u2019s sarcoma\/primitive neuroectodermal tumor in formalin-fixed paraffin-embedded tissues by RT-PCR and fluorescence in situ hybridization","volume":"14","author":"Qian","year":"2005","journal-title":"Diagn Mol Pathol."}],"container-title":["International Journal of Gynecological Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2FIGC.0b013e3181acae33","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24154990?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24154990?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1111\/IGC.0b013e3181acae33","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T01:12:39Z","timestamp":1753233159000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1048891X24154990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S1048891X24154990"],"URL":"https:\/\/doi.org\/10.1111\/igc.0b013e3181acae33","relation":{},"ISSN":["1048-891X"],"issn-type":[{"value":"1048-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary Vulvar Ewing Sarcoma\/Primitive Neuroectodermal Tumor","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecological Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/IGC.0b013e3181acae33","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright Copyright \u00a9 2009 by IGCS and ESGO.","name":"copyright","label":"Copyright"}]}}