{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:18:07Z","timestamp":1791271087866,"version":"4.1.0"},"reference-count":30,"publisher":"Hindawi Limited","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":873,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Clin Pract"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1111\/ijcp.12113","type":"journal-article","created":{"date-parts":[[2013,4,11]],"date-time":"2013-04-11T09:42:11Z","timestamp":1365673331000},"page":"427-434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Repeated intravesical onabotulinumtoxinA injections are effective in treatment of refractory interstitial cystitis\/bladder pain syndrome"],"prefix":"10.1155","volume":"67","author":[{"given":"H.-C.","family":"Kuo","sequence":"first","affiliation":[{"name":"Department of Urology; Buddhist Tzu Chi General Hospital and Tzu Chi University; Hualien Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2013,4,11]]},"reference":[{"issue":"Suppl. 6A","key":"10.1111\/ijcp.12113-BIB0001|ijcp12113-cit-0001","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0090-4295(01)01112-8","article-title":"Clinical highlights of the national Institute of Diabetes and Digestive and Kidney Diseases\/Interstitial Cystitis Association scientific conference on interstitial cystitis","volume":"57","author":"Hanno","year":"2001","journal-title":"Urology"},{"key":"10.1111\/ijcp.12113-BIB0002|ijcp12113-cit-0002","doi-asserted-by":"crossref","first-page":"E136","DOI":"10.1111\/j.1464-410X.2010.09911.x","article-title":"Higher levels of cell apoptosis and abnormal E-cadherin expression in the urothelium are associated with inflammation in patients with interstitial cystitis\/painful bladder syndrome","volume":"108","author":"Shie","year":"2011","journal-title":"BJU Int"},{"key":"10.1111\/ijcp.12113-BIB0003|ijcp12113-cit-0003","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1111\/j.1464-410X.2003.04722.x","article-title":"Parallel changes in bladder suburothelial vanilloid receptor TRPV1 and pan-neuronal marker PGP9.5 immunoreactivity in patients with neurogenic detrusor overactivity after intravesical resiniferatoxin treatment","volume":"93","author":"Brady","year":"2004","journal-title":"BJU Int"},{"key":"10.1111\/ijcp.12113-BIB0004|ijcp12113-cit-0004","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/35039519","article-title":"Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice","volume":"407","author":"Cockayne","year":"2000","journal-title":"Nature"},{"key":"10.1111\/ijcp.12113-BIB0005|ijcp12113-cit-0005","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00240-002-0291-0","article-title":"Botulinum toxin type A may improve bladder function in a rat chemical cystitis model","volume":"30","author":"Cayan","year":"2003","journal-title":"Urol Res"},{"key":"10.1111\/ijcp.12113-BIB0006|ijcp12113-cit-0006","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/ncpuro0408","article-title":"Mechanisms of disease: the role of nerve growth factor in the pathophysiology of bladder disorders","volume":"3","author":"Steers","year":"2006","journal-title":"Nat Clin Pract Urol"},{"key":"10.1111\/ijcp.12113-BIB0007|ijcp12113-cit-0007","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/S0022-5347(05)00322-8","article-title":"Botulinum toxin type a inhibits calcitonin gene-related peptide release from isolated rat bladder","volume":"175","author":"Rapp","year":"2006","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0008|ijcp12113-cit-0008","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1097\/01.ju.0000137844.77524.97","article-title":"Intravesical botulinum toxin A administration produces analgesia against acetic acid induced bladder pain response in rats","volume":"172","author":"Chuang","year":"2004","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0009|ijcp12113-cit-0009","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1016\/S0022-5347(06)00258-8","article-title":"Botulinum-A toxin injections into the detrusor muscle decrease nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity","volume":"175","author":"Giannantoni","year":"2006","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0010|ijcp12113-cit-0010","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.neuint.2004.06.001","article-title":"Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury","volume":"45","author":"Khera","year":"2004","journal-title":"Neurochem Int"},{"key":"10.1111\/ijcp.12113-BIB0011|ijcp12113-cit-0011","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/01.ju.0000169481.42259.54","article-title":"Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injection of botulinum A toxin for human detrusor overactivity","volume":"173","author":"Apostolidis","year":"2005","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0012|ijcp12113-cit-0012","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.eururo.2003.12.004","article-title":"European experience of 200 cases treated with botulinum-A toxin injections into the detrusor muscle for urinary incontinence due to neurogenic detrusor overactivity","volume":"45","author":"Reitz","year":"2004","journal-title":"Eur Urol"},{"key":"10.1111\/ijcp.12113-BIB0013|ijcp12113-cit-0013","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.urology.2004.06.073","article-title":"Botulinum toxin A has antinociceptive effects in treating interstitial cystitis","volume":"64","author":"Smith","year":"2004","journal-title":"Urology"},{"key":"10.1111\/ijcp.12113-BIB0014|ijcp12113-cit-0014","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000087173","article-title":"Preliminary results of suburothelial injection of botulinum A toxin in the treatment of chronic interstitial cystitis","volume":"75","author":"Kuo","year":"2005","journal-title":"Urol Int"},{"key":"10.1111\/ijcp.12113-BIB0015|ijcp12113-cit-0015","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.eururo.2005.12.002","article-title":"Botulinum A toxin intravesical injections in the treatment of painful bladder syndrome: A pilot study","volume":"49","author":"Giannantoni","year":"2006","journal-title":"Eur Urol"},{"key":"10.1111\/ijcp.12113-BIB0016|ijcp12113-cit-0016","first-page":"414","article-title":"Botulinum toxin type A (BTX-A) reduces inflammatory pain in the rat formalin model","volume":"20","author":"Cui","year":"2000","journal-title":"Cephalalgia"},{"key":"10.1111\/ijcp.12113-BIB0017|ijcp12113-cit-0017","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.juro.2007.10.032","article-title":"Botulinum A toxin intravesical injection in patients with painful bladder syndrome: 1-year followup","volume":"179","author":"Giannantoni","year":"2008","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0018|ijcp12113-cit-0018","first-page":"631","volume-title":"Campbell's Urology","author":"Hanno","year":"1998","edition":"7"},{"key":"10.1111\/ijcp.12113-BIB0019|ijcp12113-cit-0019","unstructured":"NIDDK workshop of interstitial cystitis Besthesda, Maryland, USA 1987"},{"issue":"Suppl. 1","key":"10.1111\/ijcp.12113-BIB0020|ijcp12113-cit-0020","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0090-4295(01)01126-8","article-title":"Psychometric validation of the O'Leary-Sant interstitial cystitis symptom index in a clinical trial of pentosan polysulfate sodium","volume":"57","author":"Lubeck","year":"2001","journal-title":"Urology"},{"key":"10.1111\/ijcp.12113-BIB0021|ijcp12113-cit-0021","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.urology.2004.10.071","article-title":"Randomized, double-blind, dose-ranging study of pentosan polysulfate sodium for interstitial cystitis","volume":"65","author":"Nickel","year":"2005","journal-title":"Urology"},{"key":"10.1111\/ijcp.12113-BIB0022|ijcp12113-cit-0022","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1097\/01.ju.0000083020.06212.3d","article-title":"A pilot clinical trial of oral pentosan polysulphate and oral hydroxyzine in patients with interstitial cystitis","volume":"170","author":"Sant","year":"2003","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0023|ijcp12113-cit-0023","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/nau.10052","article-title":"The standardisation of terminology of lower urinary tract function: Report from the Standardisation Sub-committee of the International Continence Society","volume":"21","author":"Abrams","year":"2002","journal-title":"Neurourol Urodyn"},{"key":"10.1111\/ijcp.12113-BIB0024|ijcp12113-cit-0024","first-page":"432","article-title":"The potassium sensitivity test: a new gold standard for diagnosing and understanding the pathophysiology of interstitial cystitis","volume":"182","author":"Parsons","year":"2009","journal-title":"J Urol"},{"key":"10.1111\/ijcp.12113-BIB0025|ijcp12113-cit-0025","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1464-410X.2009.08495.x","article-title":"Comparison of intravesical botulinum toxin type A injections plus hydrodistention with hydrodistention alone for the treatment of refractory interstitial cystitis\/painful bladder syndrome","volume":"104","author":"Kuo","year":"2009","journal-title":"BJU Int"},{"key":"10.1111\/ijcp.12113-BIB0026|ijcp12113-cit-0026","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pain.2003.10.008","article-title":"Subcutaneous administration of botulinum toxin A reduces formalin-induced pain","volume":"107","author":"Cui","year":"2004","journal-title":"Pain"},{"key":"10.1111\/ijcp.12113-BIB0027|ijcp12113-cit-0027","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.urology.2007.04.038","article-title":"Intravesical botulinum toxin A injections plus hydrodistension can reduce nerve growth factor production and control bladder pain in interstitial cystitis","volume":"70","author":"Liu","year":"2007","journal-title":"Urology"},{"key":"10.1111\/ijcp.12113-BIB0028|ijcp12113-cit-0028","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.eururo.2010.02.031","article-title":"Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome\/interstitial cystitis","volume":"58","author":"Pinto","year":"2010","journal-title":"Eur Urol"},{"key":"10.1111\/ijcp.12113-BIB0029|ijcp12113-cit-0029","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00345-007-0174-7","article-title":"Increased number of apoptotic endothelial cells in bladder of interstitial cystitis patients","volume":"25","author":"Yamada","year":"2007","journal-title":"World J Urol"},{"key":"10.1111\/ijcp.12113-BIB0030|ijcp12113-cit-0030","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/j.1464-410X.2009.08467.x","article-title":"Increased vascular endothelial growth factor expression in patients with bladder pain syndrome\/ interstitial cystitis: its association with pain severity and glomerulations","volume":"104","author":"Kiuchi","year":"2009","journal-title":"BJU Int"}],"container-title":["International Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijcp.12113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T06:06:38Z","timestamp":1643349998000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijcp.12113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,11]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"URL":"https:\/\/doi.org\/10.1111\/ijcp.12113","relation":{},"ISSN":["1368-5031"],"issn-type":[{"value":"1368-5031","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4,11]]},"assertion":[{"value":"2013-04-11","name":"published_online","label":"Published Online","group":{"name":"publication_history","label":"Publication History"}}]}}