{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:10:39Z","timestamp":1771467039130,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":454,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002101","name":"Division of Health Sciences, University of Otago","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002101","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Clin Pract"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1111\/ijcp.12471","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T02:07:27Z","timestamp":1401934047000},"page":"1209-1215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Aortic valve disease"],"prefix":"10.1155","volume":"68","author":[{"given":"J.","family":"Rayner","sequence":"first","affiliation":[{"name":"Department of Cardiology; Oxford University Hospitals NHS Trust; Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Coffey","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Oxford University Hospitals NHS Trust; Oxford UK"},{"name":"Cardiology Research Group; Department of Medicine; University of Otago; Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Newton","sequence":"additional","affiliation":[{"name":"Cardiology Research Group; Department of Medicine; University of Otago; Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. D.","family":"Prendergast","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Oxford University Hospitals NHS Trust; Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"10.1111\/ijcp.12471-BIB0001|ijcp12471-cit-0001","doi-asserted-by":"crossref","first-page":"9540","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet"},{"key":"10.1111\/ijcp.12471-BIB0002|ijcp12471-cit-0002","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/0735-1097(93)90249-Z","article-title":"Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample","volume":"21","author":"Lindroos","year":"1993","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0003|ijcp12471-cit-0003","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1136\/heartjnl-2012-302265","article-title":"The evolving epidemiology of valvular aortic stenosis. The Tromso Study","volume":"99","author":"Eveborn","year":"2013","journal-title":"Heart"},{"key":"10.1111\/ijcp.12471-BIB0004|ijcp12471-cit-0004","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on valvular heart disease","volume":"24","author":"Iung","year":"2003","journal-title":"Eur Heart J"},{"issue":"562-7.","key":"10.1111\/ijcp.12471-BIB0005|ijcp12471-cit-0005","first-page":"e2","article-title":"Lack of progress in valvular heart disease in the pre-transcatheter aortic valve replacement era: increasing deaths and minimal change in mortality rate over the past three decades","volume":"167","author":"Coffey","year":"2014","journal-title":"Am Heart J"},{"key":"10.1111\/ijcp.12471-BIB0006|ijcp12471-cit-0006","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.jacc.2012.02.093","article-title":"Calcific aortic stenosis: a disease of the valve and the myocardium","volume":"60","author":"Dweck","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"Suppl. E","key":"10.1111\/ijcp.12471-BIB0007|ijcp12471-cit-0007","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/eurheartj\/9.suppl_E.57","article-title":"The natural history of aortic stenosis","volume":"9","author":"Horstkotte","year":"1988","journal-title":"Eur Heart J"},{"key":"10.1111\/ijcp.12471-BIB0008|ijcp12471-cit-0008","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1093\/eurheartj\/ehs109","article-title":"Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"33","author":"Vahanian","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1111\/ijcp.12471-BIB0009|ijcp12471-cit-0009","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.jacc.2012.06.051","article-title":"Low-flow, low-gradient aortic stenosis with normal and depressed left ventricular ejection fraction","volume":"60","author":"Pibarot","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0010|ijcp12471-cit-0010","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0002-9149(00)80078-8","article-title":"Usefulness of dobutamine echocardiography in distinguishing severe from nonsevere valvular aortic stenosis in patients with depressed left ventricular function and low transvalvular gradients","volume":"75","author":"deFilippi","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0011|ijcp12471-cit-0011","doi-asserted-by":"crossref","first-page":"2856","DOI":"10.1161\/CIRCULATIONAHA.106.668681","article-title":"Paradoxical low-flow, low-gradient severe aortic stenosis despite preserved ejection fraction is associated with higher afterload and reduced survival","volume":"115","author":"Hachicha","year":"2007","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0012|ijcp12471-cit-0012","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1161\/CIRCULATIONAHA.113.003695","article-title":"Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival","volume":"128","author":"Eleid","year":"2013","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0013|ijcp12471-cit-0013","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1093\/eurheartj\/eht408","article-title":"Clinical outcomes of patients with low-flow, low-gradient, severe aortic stenosis and either preserved or reduced ejection fraction undergoing transcatheter aortic valve implantation","volume":"34","author":"O'Sullivan","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1111\/ijcp.12471-BIB0014|ijcp12471-cit-0014","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/CIRCULATIONAHA.112.001094","article-title":"Impact of aortic valve replacement on outcome of symptomatic patients with severe aortic stenosis with low gradient and preserved left ventricular ejection fraction","volume":"128","author":"Ozkan","year":"2013","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0015|ijcp12471-cit-0015","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1161\/01.CIR.0000079171.43055.46","article-title":"Low-gradient aortic stenosis: operative risk stratification and predictors for long-term outcome: a multicenter study using dobutamine stress hemodynamics","volume":"108","author":"Monin","year":"2003","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0016|ijcp12471-cit-0016","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1161\/CIRCULATIONAHA.105.568824","article-title":"Influence of preoperative left ventricular contractile reserve on postoperative ejection fraction in low-gradient aortic stenosis","volume":"113","author":"Quere","year":"2006","journal-title":"Circulation"},{"issue":"Suppl. 4","key":"10.1111\/ijcp.12471-BIB0017|ijcp12471-cit-0017","doi-asserted-by":"crossref","first-page":"iv14","DOI":"10.1136\/heartjnl-2012-302392","article-title":"The art of assessing aortic stenosis","volume":"98","author":"Rajani","year":"2012","journal-title":"Heart"},{"key":"10.1111\/ijcp.12471-BIB0018|ijcp12471-cit-0018","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1161\/CIRCULATIONAHA.108.847772","article-title":"Impact of myocardial fibrosis in patients with symptomatic severe aortic stenosis","volume":"120","author":"Weidemann","year":"2009","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0019|ijcp12471-cit-0019","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jacc.2009.12.074","article-title":"Prognostic significance of myocardial fibrosis quantification by histopathology and magnetic resonance imaging in patients with severe aortic valve disease","volume":"56","author":"Azevedo","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0020|ijcp12471-cit-0020","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.jacc.2011.03.064","article-title":"Midwall fibrosis is an independent predictor of mortality in patients with aortic stenosis","volume":"58","author":"Dweck","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0021|ijcp12471-cit-0021","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1136\/heartjnl-2012-303052","article-title":"Human non-contrast T1 values and correlation with histology in diffuse fibrosis","volume":"99","author":"Bull","year":"2013","journal-title":"Heart"},{"key":"10.1111\/ijcp.12471-BIB0022|ijcp12471-cit-0022","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1136\/hrt.2010.198853","article-title":"Measurement of aortic valve calcification using multislice computed tomography: correlation with haemodynamic severity of aortic stenosis and clinical implication for patients with low ejection fraction","volume":"97","author":"Cueff","year":"2011","journal-title":"Heart"},{"issue":"125","key":"10.1111\/ijcp.12471-BIB0023|ijcp12471-cit-0023","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1161\/CIRCULATIONAHA.111.073452","article-title":"Look more closely at the valve: imaging calcific aortic valve disease","volume":"125","author":"Aikawa","year":"2012","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0024|ijcp12471-cit-0024","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/CIRCULATIONAHA.111.051052","article-title":"Assessment of valvular calcification and inflammation by positron emission tomography in patients with aortic stenosis","volume":"125","author":"Dweck","year":"2012","journal-title":"Circulation"},{"issue":"Suppl. 4","key":"10.1111\/ijcp.12471-BIB0025|ijcp12471-cit-0025","doi-asserted-by":"crossref","first-page":"iv23","DOI":"10.1136\/heartjnl-2012-302399","article-title":"Contemporary management of aortic stenosis: surgical aortic valve replacement remains the gold standard","volume":"98","author":"Walther","year":"2012","journal-title":"Heart"},{"key":"10.1111\/ijcp.12471-BIB0026|ijcp12471-cit-0026","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1056\/NEJMoa043876","article-title":"A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis","volume":"352","author":"Cowell","year":"2005","journal-title":"N Engl J Med"},{"issue":"359","key":"10.1111\/ijcp.12471-BIB0027|ijcp12471-cit-0027","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJMoa0804602","article-title":"Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis","volume":"25","author":"Rossebo","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0028|ijcp12471-cit-0028","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1161\/CIRCULATIONAHA.109.900027","article-title":"Effect of lipid lowering with rosuvastatin on progression of aortic stenosis: results of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) trial","volume":"121","author":"Chan","year":"2010","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0029|ijcp12471-cit-0029","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.1016\/j.ahj.2003.10.017","article-title":"Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: Symptomatic Cardiac Obstruction-Pilot Study of Enalapril in Aortic Stenosis (SCOPE-AS)","volume":"147","author":"Chockalingam","year":"2004","journal-title":"Am Heart J"},{"key":"10.1111\/ijcp.12471-BIB0030|ijcp12471-cit-0030","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1038\/sj.bjp.0703467","article-title":"Heart failure development in rats with ascending aortic constriction and angiotensin-converting enzyme inhibition","volume":"130","author":"Turcani","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1111\/ijcp.12471-BIB0031|ijcp12471-cit-0031","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1161\/01.CIR.0000124794.16806.E3","article-title":"Percutaneous approaches to valvular disease","volume":"109","author":"Vahanian","year":"2004","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0032|ijcp12471-cit-0032","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","article-title":"Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery","volume":"363","author":"Leon","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0033|ijcp12471-cit-0033","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus surgical aortic-valve replacement in high-risk patients","volume":"364","author":"Smith","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0034|ijcp12471-cit-0034","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1056\/NEJMoa1202277","article-title":"Transcatheter aortic-valve replacement for inoperable severe aortic stenosis","volume":"366","author":"Makkar","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0035|ijcp12471-cit-0035","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1056\/NEJMoa1200384","article-title":"Two-year outcomes after transcatheter or surgical aortic-valve replacement","volume":"366","author":"Kodali","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0036|ijcp12471-cit-0036","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1056\/NEJMoa1400590","article-title":"Transcatheter aortic-valve replacement with a self-expanding prosthesis","volume":"370","author":"Adams","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12471-BIB0037|ijcp12471-cit-0037","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jacc.2011.10.868","article-title":"Improvements in transcatheter aortic valve implantation outcomes in lower surgical risk patients: a glimpse into the future","volume":"59","author":"Lange","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0038|ijcp12471-cit-0038","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1161\/01.CIR.84.4.1625","article-title":"Serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function","volume":"84","author":"Bonow","year":"1991","journal-title":"Circulation"},{"key":"10.1111\/ijcp.12471-BIB0039|ijcp12471-cit-0039","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0735-1097(97)00205-2","article-title":"Optimizing timing of surgical correction in patients with severe aortic regurgitation: role of symptoms","volume":"30","author":"Klodas","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/ijcp.12471-BIB0040|ijcp12471-cit-0040","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ejcts.2009.06.021","article-title":"Aortic valve repair leads to a low incidence of valve-related complications","volume":"37","author":"Aicher","year":"2010","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1111\/ijcp.12471-BIB0041|ijcp12471-cit-0041","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.jacc.2013.01.018","article-title":"Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation","volume":"61","author":"Roy","year":"2013","journal-title":"J Am Coll Cardiol"}],"container-title":["International Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijcp.12471","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T06:08:35Z","timestamp":1643350115000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijcp.12471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,4]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"URL":"https:\/\/doi.org\/10.1111\/ijcp.12471","relation":{},"ISSN":["1368-5031"],"issn-type":[{"value":"1368-5031","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6,4]]},"assertion":[{"value":"2014-06-04","name":"published_online","label":"Published Online","group":{"name":"publication_history","label":"Publication History"}}]}}