{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:44:31Z","timestamp":1785411871741,"version":"3.56.0"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":123,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004572","name":"National Health and Family Planning Commission of the People's Republic of China","doi-asserted-by":"publisher","award":["201302009"],"award-info":[{"award-number":["201302009"]}],"id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004572","name":"National Health and Family Planning Commission of the People's Republic of China","doi-asserted-by":"publisher","award":["201002004"],"award-info":[{"award-number":["201002004"]}],"id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Clin Pract"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1111\/ijcp.12662","type":"journal-article","created":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T02:10:21Z","timestamp":1430878221000},"page":"16-22","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"supplement S183","title":["Effect of<i>CYP3A5<\/i>polymorphism on the pharmacokinetics of tacrolimus and acute rejection in renal transplant recipients: experience at a single centre"],"prefix":"10.1155","volume":"69","author":[{"given":"Y.","family":"Cheng","sequence":"first","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Li","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Meng","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Yang","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Xu","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Yu","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Zhao","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Liu","sequence":"additional","affiliation":[{"name":"Organ Transplant Unit of the First Hospital of China Medical University; Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,5]]},"reference":[{"key":"10.1111\/ijcp.12662-BIB0001|ijcp12662-cit-0001","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.bbagen.2006.09.024","article-title":"The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks","volume":"1770","author":"Plant","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"10.1111\/ijcp.12662-BIB0002|ijcp12662-cit-0002","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1373\/clinchem.2005.050047","article-title":"Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus","volume":"51","author":"Kamdem","year":"2005","journal-title":"Clin Chem"},{"key":"10.1111\/ijcp.12662-BIB0003|ijcp12662-cit-0003","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/86882","article-title":"Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression","volume":"27","author":"Kuehl","year":"2001","journal-title":"Nat Genet"},{"key":"10.1111\/ijcp.12662-BIB0004|ijcp12662-cit-0004","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1097\/00008571-200112000-00005","article-title":"The genetic determinants of the CYP3A5 polymorphism","volume":"11","author":"Hustert","year":"2001","journal-title":"Pharmacogenetics"},{"key":"10.1111\/ijcp.12662-BIB0005|ijcp12662-cit-0005","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1742-7843.2008.00327.x","article-title":"Influence of CYP3A5 genetic polymorphism on tacrolimus daily dose requirements and acute rejection in renal graft recipients","volume":"103","author":"Quteineh","year":"2008","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.1111\/ijcp.12662-BIB0006|ijcp12662-cit-0006","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.transproceed.2009.01.050","article-title":"Genetic polymorphisms in CYP3A5 and MDR1 genes and their correlations with plasma levels of tacrolimus and cyclosporine in renal transplant recipients","volume":"41","author":"Mendes","year":"2009","journal-title":"Transplant Proc"},{"key":"10.1111\/ijcp.12662-BIB0007|ijcp12662-cit-0007","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0009-9236(03)00168-1","article-title":"Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus","volume":"74","author":"Hesselink","year":"2003","journal-title":"Clin Pharmacol Ther"},{"key":"10.1111\/ijcp.12662-BIB0008|ijcp12662-cit-0008","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1056\/NEJMra020526","article-title":"Pharmacogenomics-drug disposition, drug targets, and side effects","volume":"348","author":"Evans","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1111\/ijcp.12662-BIB0009|ijcp12662-cit-0009","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.transproceed.2005.01.077","article-title":"Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus","volume":"37","author":"Zhao","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1111\/ijcp.12662-BIB0010|ijcp12662-cit-0010","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/j.1365-2710.2010.01206.x","article-title":"Association of ABCB1, CYP3A4*18B and CYP3A5*3 genotypes with the pharmacokinetics of tacrolimus in healthy Chinese subjects: a population pharmacokinetic analysis","volume":"36","author":"Shi","year":"2011","journal-title":"J Clin Pharm Ther"},{"key":"10.1111\/ijcp.12662-BIB0011|ijcp12662-cit-0011","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2710.2007.00791.x","article-title":"Genetic polymorphisms in MDR1 and CYP3A5 and MDR1 haplotype in mainland Chinese Han, Uygur and Kazakh ethnic groups","volume":"32","author":"Li","year":"2007","journal-title":"J Clin Pharm Ther"},{"key":"10.1111\/ijcp.12662-BIB0012|ijcp12662-cit-0012","doi-asserted-by":"crossref","first-page":"e86206","DOI":"10.1371\/journal.pone.0086206","article-title":"Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipients","volume":"9","author":"Li","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1111\/ijcp.12662-BIB0013|ijcp12662-cit-0013","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.transproceed.2009.11.028","article-title":"Pharmacogenetics of immunosuppressant polymorphism of CYP3A5 in renal transplant recipients","volume":"42","author":"Larriba","year":"2010","journal-title":"Transplant Proc"},{"key":"10.1111\/ijcp.12662-BIB0014|ijcp12662-cit-0014","doi-asserted-by":"crossref","first-page":"E272","DOI":"10.1111\/ctr.12101","article-title":"Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism-a prospective, randomized, controlled study","volume":"27","author":"Chen","year":"2013","journal-title":"Clin Transplant"},{"key":"10.1111\/ijcp.12662-BIB0015|ijcp12662-cit-0015","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/FTD.0b013e31829f1ab8","article-title":"Population pharmacokinetics of tacrolimus in adult kidney transplant patients: impact of CYP3A5 genotype on starting dose","volume":"36","author":"Bergmann","year":"2014","journal-title":"Ther Drug Monit"},{"key":"10.1111\/ijcp.12662-BIB0016|ijcp12662-cit-0016","first-page":"878","article-title":"Effect of CYP3A4*18B, CYP3A5*3 gene polymorphism on dosage and concentration of tacrolimus in renal transplant patients","volume":"47","author":"Zhu","year":"2012","journal-title":"Yao Xue Xue Bao"},{"key":"10.1111\/ijcp.12662-BIB0017|ijcp12662-cit-0017","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/FPC.0b013e3283557c74","article-title":"The effect of CYP3A5 6986A>G and ABCB1 3435C>T on tacrolimus dose-adjusted trough levels and acute rejection rates in renal transplant patients: a systematic review and meta-analysis","volume":"22","author":"Terrazzino","year":"2012","journal-title":"Pharmacogenet Genomics"},{"key":"10.1111\/ijcp.12662-BIB0018|ijcp12662-cit-0018","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1111\/j.1600-6143.2004.00435.x","article-title":"The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation","volume":"4","author":"MacPhee","year":"2004","journal-title":"Am J Transplant"}],"container-title":["International Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijcp.12662","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T07:56:03Z","timestamp":1651910163000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijcp.12662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":18,"URL":"https:\/\/doi.org\/10.1111\/ijcp.12662","relation":{},"ISSN":["1368-5031"],"issn-type":[{"value":"1368-5031","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"2015-05-05","name":"published_online","label":"Published Online","group":{"name":"publication_history","label":"Publication History"}}]}}