{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:26:10Z","timestamp":1767165970095,"version":"build-2238731810"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Clinical Practice"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To describe the clinical characteristics and outcomes of adult patients with severe COVID\u201019, with the exploration of risk factors for mortality in the hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 20 adult patients diagnosed with COVID\u201019 admitted to the ICU of DHQ Hospital, Faisalabad (Pakistan). Patients were categorised into the survival group and the death group according to the outcome. We retrieved demographics, clinical manifestations and signs, laboratory indicators, treatment measures and clinical outcomes from the medical record, and summarised the clinical characteristics and outcomes of these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The average age of patients was 70\u00a0\u00b1\u00a012\u00a0years, of which 40% were male. They were admitted to the ICU 11\u00a0days after the onset of symptoms. The most common symptoms on admission were cough (19 cases, 95%), fatigue or myalgia (18 cases, 90%), fever (17 cases, 85%) and dyspnoea (16 cases, 80%). Eleven (55%) patients had underlying diseases, of which hypertension was the most common (11 cases, 55%), followed by cardiovascular disease (4 cases, 20%) and diabetes (3 cases, 15%). Six patients (30%) received invasive mechanical ventilation and continuous renal replacement therapy and eventually died. Acute heart injury was the most common complication (19 cases, 95%). Ten (50%) patients died between 2 and 19\u00a0days after admission to the ICU. Compared with dead patients, the average body weight of surviving patients was lower (61.70\u00a0\u00b1\u00a02.36 vs 68.60\u00a0\u00b1\u00a07.15,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.01), Glasgow Coma Scale score was higher (14.69\u00a0\u00b1\u00a00.70 vs 12.70\u00a0\u00b1\u00a02.45,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.03), with fewer concurrent shocks (2 vs 10,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.001) and acute respiratory distress syndrome (2 vs 10,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The mortality rate is high in critically ill patients with COVID\u201019. Lower Glasgow Coma Scale, higher body weight and decreased lymphocyte count appear to be potential risk factors for the death of patients with COVID\u201019 in the ICU.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijcp.14152","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T03:44:25Z","timestamp":1615952665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Retracted:<\/i>\n                    Clinical characteristics and outcomes of patients with COVID\u201019 pneumonia admitted to an intensive care unit in Faisalabad, Pakistan"],"prefix":"10.1155","volume":"75","author":[{"given":"Noor","family":"Gul","sequence":"first","affiliation":[{"name":"District Headquarter Hospital Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umer","family":"Usman","sequence":"additional","affiliation":[{"name":"District Headquarter Hospital Faisalabad Pakistan"},{"name":"Faisalabad Medical University Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umair","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Allied Hospital Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4585-4870","authenticated-orcid":false,"given":"Majid","family":"Ali","sequence":"additional","affiliation":[{"name":"College of Pharmacy Umm Al\u2010Qura University Makkah Saudi Arabia"},{"name":"Faculty of Health and Medical Sciences University of Adelaide Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aamir","family":"Shaukat","sequence":"additional","affiliation":[{"name":"District Headquarter Hospital Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehar Muhammad","family":"Imran","sequence":"additional","affiliation":[{"name":"District Headquarter Hospital Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmni.2020.100681"},{"key":"e_1_2_9_3_1","unstructured":"World Health Organization.Coronavirus disease (COVID\u201019) pandemic.2020.https:\/\/www.who.int\/emergencies\/diseases\/novel\u2010coronavirus\u20102019. 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