{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:43:16Z","timestamp":1777524196229,"version":"3.51.4"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T00:00:00Z","timestamp":1629244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T00:00:00Z","timestamp":1629244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Clin Pract"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1111\/ijcp.14649","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T18:36:03Z","timestamp":1627324563000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Insufficient evidence for vitamin D use in COVID\u201019: A rapid systematic review"],"prefix":"10.1155","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0863-6500","authenticated-orcid":false,"given":"Aline Pereira","family":"Rocha","sequence":"first","affiliation":[{"name":"Discipline of Evidence\u2010Based Health Escola Paulista de Medicina (EPM)Universidade Federal de S\u00e3o Paulo (Unifesp) S\u00e3o Paulo Brazil"},{"name":"Cochrane Brazil S\u00e3o Paulo (SP) Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro Nagib","family":"Atallah","sequence":"additional","affiliation":[{"name":"Discipline of Evidence\u2010Based Health Escola Paulista de Medicina (EPM)Universidade Federal de S\u00e3o Paulo (Unifesp) S\u00e3o Paulo Brazil"},{"name":"Cochrane Brazil S\u00e3o Paulo (SP) Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Mendes","family":"Aldrighi","sequence":"additional","affiliation":[{"name":"Faculdade de Sa\u00fade P\u00fablica Faculdade de Ci\u00eancias M\u00e9dicas Santa Casa USP S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9a Larissa Ribeiro","family":"Pires","sequence":"additional","affiliation":[{"name":"Universidade de PernambucoUniversidade Federal da Para\u00edba (UFPB) Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Eduarda","family":"Santos Puga","sequence":"additional","affiliation":[{"name":"Discipline of Evidence\u2010Based Health Escola Paulista de Medicina (EPM)Universidade Federal de S\u00e3o Paulo (Unifesp) S\u00e3o Paulo Brazil"},{"name":"Cochrane Brazil S\u00e3o Paulo (SP) Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-877X","authenticated-orcid":false,"given":"Ana Carolina Pereira Nunes","family":"Pinto","sequence":"additional","affiliation":[{"name":"Discipline of Evidence\u2010Based Health Escola Paulista de Medicina (EPM)Universidade Federal de S\u00e3o Paulo (Unifesp) S\u00e3o Paulo Brazil"},{"name":"Cochrane Brazil S\u00e3o Paulo (SP) Brazil"},{"name":"Fulbright Alumna University of Pittsburgh Pittsburgh PA USA"},{"name":"Biological and Health Sciences Department Universidade Federal do Amap\u00e1\u2014AP Macapa Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,18]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization. Coronavirus disease (COVID\u201019). Weekly Epidemiological Update. Data as received by WHO from national authorities as of 27 September 2020 10 am CEST 2020.https:\/\/www.who.int\/docs\/default\u2010source\/coronaviruse\/situation\u2010reports\/20200928\u2010weekly\u2010epi\u2010update.pdf?sfvrsn=9e354665_6"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2020.198148"},{"key":"e_1_2_10_4_1","first-page":"1","article-title":"Vitamin D and COVID\u201019 infection and mortality in UK Biobank","volume":"26","author":"Hastie CE","year":"2020","journal-title":"Eur J Nutr"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15752"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i6583"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119536604"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01570-8"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16649"},{"key":"e_1_2_10_10_1","article-title":"Prevalence and predictors of vitamin D\u2010deficiency in frail older hospitalized patients","volume":"219","author":"Boettger SF","year":"2018","journal-title":"BMC Geriatr"},{"key":"e_1_2_10_11_1","unstructured":"GarrittyC GartlehnerG KamelC et al. Cochrane Rapid Reviews Interim Guidance from the Cochrane Rapid Reviews Methods Group 2020.https:\/\/methods.cochrane.org\/rapidreviews\/sites\/methods.cochrane.org.rapidreviews\/files\/public\/uploads\/cochrane_rr_\u2010_guidance\u201023mar2020\u2010v1.pdf"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7454.1490"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2020.105751"},{"key":"e_1_2_10_14_1","article-title":"Short term, high\u2010dose vitamin D supplementation for COVID\u201019 disease: a randomised, placebo\u2010controlled, study (SHADE study)","volume":"12","author":"Rastogi A","year":"2020","journal-title":"Postgrad Med J"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26848"},{"key":"e_1_2_10_16_1","unstructured":"NCT04344041. Cholecalciferol to Improve the Outcomes of COVID\u201019 Patients (CARED).https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04411446?term=NCT04411446&draw=2&rank=1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-020-04547-0"},{"key":"e_1_2_10_18_1","unstructured":"NCT04344041. COvid\u201019 and vitamin D supplementation: a multicenter randomized controlled trial of high dose versus standard dose vitamin D3 in high\u2010risk COVID\u201019 patients (CoVitTrial).https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04344041"},{"key":"e_1_2_10_19_1","unstructured":"NCT04351490. Impact of zinc and vitamin D3 supplementation on the survival of aged patients infected with COVID\u201019.https:\/\/clinicaltrials.gov\/show\/NCT04351490"},{"key":"e_1_2_10_20_1","unstructured":"NCT04395768. International alliance study of therapies to prevent progression of COVID\u201019.https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04395768"},{"key":"e_1_2_10_21_1","unstructured":"NCT04476745. The effect of D3 on selected cytokines involved in cytokine storm in the Covid\u201019 uninfected Jordanian people.https:\/\/clinicaltrials.gov\/show\/NCT04476745"},{"key":"e_1_2_10_22_1","unstructured":"NCT04363840. The LEAD COVID\u201019 trial: low\u2010risk early aspirin and vitamin D to reduce COVID\u201019 hospitalizations.https:\/\/clinicaltrials.gov\/show\/NCT04363840"},{"key":"e_1_2_10_23_1","unstructured":"NCT04482686. Trial of combination therapy to treat COVID\u201019 infection.https:\/\/clinicaltrials.gov\/show\/NCT04482686"},{"key":"e_1_2_10_24_1","unstructured":"NCT04385940. Vitamin D and COVID\u201019 management.https:\/\/clinicaltrials.gov\/show\/NCT04385940"},{"key":"e_1_2_10_25_1","unstructured":"NCT04334005. Vitamin D on prevention and treatment of COVID\u201019.https:\/\/clinicaltrials.gov\/show\/NCT04334005"},{"key":"e_1_2_10_26_1","unstructured":"NCT04525820. High dose vitamin\u2010D substitution in patients with COVID\u201019: a randomized controlled multi center study.https:\/\/clinicaltrials.gov\/show\/NCT04525820"},{"key":"e_1_2_10_27_1","unstructured":"CTRI\/2020\u2010001960\u201028\/ES. Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS\u2010Cov\u20102 (COVID\u201019); 2020.https:\/\/www.clinicaltrialsregister.eu\/ctr\u2010search\/trial\/2020\u2010001960\u201028\/ES"},{"key":"e_1_2_10_28_1","unstructured":"CTRI\/2020\/06\/026189. To compare the safety and efficacy of Vitamin D with Magnesium in mild to moderate Covid 19 patients; 2020.http:\/\/www.who.int\/trialsearch\/Trial2.aspx?TrialID=CTRI\/2020\/06\/026189"},{"key":"e_1_2_10_29_1","unstructured":"2020\u2010002312\u201043\/ES. Clinical trial randomized open\u2010label to evaluate the efficacy of high\u2010dose vitamin D in patients with COVID\u201019 pneumonia; 2020.https:\/\/www.clinicaltrialsregister.eu\/ctr\u2010search\/trial\/2020\u2010002312\u201043\/ES"},{"key":"e_1_2_10_30_1","unstructured":"IRCT20200401046909N2. Evaluation of the efficacy of oral 25\u2010hydroxyvitamin D3 on COVID\u201019; 2020.https:\/\/covid\u201019.cochrane.org\/studies\/crs\u201013803024"},{"key":"e_1_2_10_31_1","unstructured":"IRCT20200411047024N1. Evaluation effect of treatment with IM D3 on clinical paraclinical symptoms and signs and inhospital outcome at patient admitted with covid19; 2020.https:\/\/www.irct.ir\/trial\/47093"},{"key":"e_1_2_10_32_1","unstructured":"2020\u2010001960\u201028. Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS\u2010Cov\u20102 (COVID\u201019).https:\/\/www.clinicaltrialsregister.eu\/ctr\u2010search\/search?query=covid\u201019+and+Vitamin+D"},{"key":"e_1_2_10_33_1","unstructured":"NCT04476680. Reducing asymptomatic infection with vitamin D in coronavirus disease; 2020.https:\/\/clinicaltrials.gov\/show\/NCT04476680"},{"key":"e_1_2_10_34_1","unstructured":"NCT04502667. Efficacy of vitamin D treatment in pediatric patients hospitalized by COVID\u201019; 2020.https:\/\/clinicaltrials.gov\/show\/NCT04502667"},{"key":"e_1_2_10_35_1","unstructured":"NCT04552951. Effect of vitamin D on morbidity and mortality of the COVID\u201019; 2020.https:\/\/clinicaltrials.gov\/show\/NCT04552951"},{"key":"e_1_2_10_36_1","unstructured":"NCT04579640. Trial of vitamin D to reduce risk and severity of COVID\u201019 and other acute respiratory infections (CORONAVIT); 2020.https:\/\/clinicaltrials.gov\/show\/NCT04579640"},{"key":"e_1_2_10_37_1","unstructured":"NCT04621058. Effectiveness of vitamin D supplements in reducing complications of COVID19; 2020.https:\/\/clinicaltrials.gov\/showNCT04621058"},{"key":"e_1_2_10_38_1","unstructured":"NCT04636086. Effect of vitamin D on hospitalized adults with COVID\u201019 infection; 2020.https:\/\/clinicaltrials.gov\/showNCT04636086"},{"key":"e_1_2_10_39_1","unstructured":"NCT04641195. Vitamin D and zinc supplementation for improving treatment outcomes among COVID\u201019 patients in India; 2020.https:\/\/clinicaltrials.gov\/showNCT04641195"},{"key":"e_1_2_10_40_1","unstructured":"NCT04733625. The effect of vitamin D therapy on morbidity and mortality in patients with SARS\u2010CoV 2 infection; 2021.https:\/\/clinicaltrials.gov\/showNCT04733625"},{"key":"e_1_2_10_41_1","unstructured":"NCT04536298. The vitamin D and COVID\u201019 trial (VIVID). A pragmatic cluster\u2010randomized design."},{"key":"e_1_2_10_42_1","article-title":"Effect of vitamin D supplementation in diagnosed cases of 2019 Novel Coronavirus; a randomized clinical trial","author":"IRCT20110726007117N11","year":"2020","journal-title":"Iran Reg Clin Trials"},{"key":"e_1_2_10_43_1","unstructured":"NCT04386850. Oral 25\u2010hydroxyvitamin D3 and COVID\u201019; 2020.https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04386850"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-135"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2020.105719"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1177\/039463200902200108"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01708"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01716-8"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03120-0"},{"key":"e_1_2_10_50_1","first-page":"123","article-title":"Intestinal absorption of 25\u2010hydroxycholecalciferol","volume":"121","author":"Stamp TCB","year":"1974","journal-title":"The Lancet"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2017.07.006"}],"container-title":["International Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijcp.14649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijcp.14649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijcp.14649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T06:09:07Z","timestamp":1643350147000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijcp.14649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,18]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/ijcp.14649"],"URL":"https:\/\/doi.org\/10.1111\/ijcp.14649","archive":["Portico"],"relation":{},"ISSN":["1368-5031","1742-1241"],"issn-type":[{"value":"1368-5031","type":"print"},{"value":"1742-1241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,18]]},"assertion":[{"value":"2020-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}