{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:08:28Z","timestamp":1788926908803,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,5,15]],"date-time":"2013-05-15T00:00:00Z","timestamp":1368576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mohs micrographic surgery is the reference standard treatment for primary cutaneous malignancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this case study is to demonstrate that <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ohs surgery may be considered as a possible treatment for a solitary metastatic tumor under the appropriate circumstances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We report a patient in whom a solitary cutaneous metastasis of renal cell carcinoma (<jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content>) was successfully treated with microscopically controlled surgical excision, and cite instances of the successful management of cutaneous metastases using the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ohs surgical technique in oncology patients reported in the literature. Patient reports and previous reviews of the subject were critically assessed. Salient features are presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Metastases to the skin are rare in <jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content>. Albeit rarely, surgical excision, particularly Mohs micrographic surgery, has been used for the removal of isolated <jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content> cutaneous metastases. In the present patient with metastatic <jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content>, a solitary cutaneous metastasis on the occipital scalp was successfully treated with <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ohs micrographic surgery. There was no recurrence of the lesion after two\u00a0years of follow\u2010up; however, the patient eventually succumbed to progressive disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We suggest that, in the appropriate setting, surgical excision of isolated cutaneous metastases using microscopically controlled margins at the time of surgery should be added to the indications for <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ohs surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12021","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T04:02:41Z","timestamp":1368676961000},"page":"856-861","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Mohs surgery in metastatic cancer: renal cell carcinoma solitary cutaneous metastasis and visceral tumor metastases to skin treated with microscopically controlled surgical excision"],"prefix":"10.1111","volume":"52","author":[{"given":"Charles L.","family":"Anzalone","sequence":"first","affiliation":[{"name":"University of Texas at Houston School of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas Medical School at Houston Houston TX USA"},{"name":"Health Center University of Houston Houston TX USA"},{"name":"Department of Dermatology University of Texas MD Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Migden","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas MD Anderson Cancer Center Houston TX USA"},{"name":"Department of Plastic Surgery University of Texas MD Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nizar 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