{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:19:17Z","timestamp":1756383557232},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T00:00:00Z","timestamp":1382054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We examined the course of cutaneous T\u2010cell lymphoma (<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>), which has been associated with chronic lymphocytic leukemia (<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>) in patients with<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A search was conducted of the master diagnosis index at our institution to identify patients with both<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>from 1980 to 2010. A retrospective chart review was then conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 14 patients with<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>, eight had mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>; two with patch stage, two with plaque stage, two with tumor stage, and two with erythrodermic stage), four had S\u00e9zary syndrome, one had natural killer cell lymphoma involving the skin, and one had peripheral T\u2010cell lymphoma involving the skin. Eight had concurrent diagnoses, five received a<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>diagnosis first, and one received a<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>diagnosis first. Ten patients were deceased at the time of data abstraction due to unknown causes (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>4), lymphoma (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>2), pneumonia (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>2),<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>(<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1), or respiratory failure (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1). Of the nine patients with concurrent or prior<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>, seven were deceased, with a median time to death of 10.2\u00a0months (range, 6\u201389\u00a0months). Of the five patients with<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>prior to<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>, three were deceased at 18, 27, and 47\u00a0months, respectively, after the<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>diagnosis. The median survival for the two groups was 12 and 47\u00a0months, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>concurrent with or prior to<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>have a worse overall survival than patients with<jats:styled-content style=\"fixed-case\">CLL<\/jats:styled-content>in whom<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>later develops. Larger studies are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12063","type":"journal-article","created":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T07:03:19Z","timestamp":1382079799000},"page":"966-970","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cutaneous<scp>T<\/scp>\u2010cell lymphoma in patients with chronic lymphocytic leukemia: clinical characteristics, temporal relationships, and survival data in a series of 14 patients at<scp>M<\/scp>ayo<scp>C<\/scp>linic"],"prefix":"10.1111","volume":"53","author":[{"given":"Michael B.","family":"Chang","sequence":"first","affiliation":[{"name":"College of Medicine Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Weaver","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry D.","family":"Brewer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,18]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"1207","article-title":"Cutaneous lymphomas","volume":"59","author":"Ingen\u2010Housz\u2010Oro S","year":"2009","journal-title":"Rev 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