{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T06:04:56Z","timestamp":1774764296026,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T00:00:00Z","timestamp":1373241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are few data regarding epidemiology and clinical features of urticarial diseases in the elderly population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      The aim of the study was to determine the clinical and laboratory characteristics of chronic idiopathic urticaria (\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      ) in the geriatric population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Electronic medical records of outpatient allergy consultations due to a diagnosis of\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      were retrospectively reviewed to collect demographic data, urticaria activity score, results of autologous serum skin test (\n                      <jats:styled-content style=\"fixed-case\">ASST<\/jats:styled-content>\n                      ), and laboratory workup.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From 1598 patients with chronic urticaria, there were 1319 (82.5%) adult (adult\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      group) and 124 (9.4%) elderly subjects (elderly\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      group). The elderly\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      group was characterized by lower prevalence (46.7%) of women compared to the adult\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      group (69.2%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.022); fewer wheals (1.4\u00a0\u00b1\u00a00.5) vs. (2.3\u00a0\u00b1\u00a00.7;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001); lower rates of concomitant symptomatic dermographism 2 (2.2%) vs. 121 (12.6%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.003); and lower rates of angioedema, 3 (14.1%) vs. 362 (37.8%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Fewer elderly patients with\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      (18.1%) than adult patients with\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      (44.7%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.019) demonstrated a positive\n                      <jats:styled-content style=\"fixed-case\">ASST<\/jats:styled-content>\n                      . There were no differences in laboratory data between the study groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>\n                      in the elderly population is nearly equally distributed in both sexes and is characterized by fewer wheals, lower rates of concomitant symptomatic dermographism, lower rates of angioedema, and lower\n                      <jats:styled-content style=\"fixed-case\">ASST<\/jats:styled-content>\n                      positivity.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.12109","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T04:32:32Z","timestamp":1373257952000},"page":"1387-1391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Clinical and laboratory features of chronic idiopathic urticaria in the elderly"],"prefix":"10.1111","volume":"52","author":[{"given":"Eli","family":"Magen","sequence":"first","affiliation":[{"name":"Leumit Health Services Barzilai Medical Center Ben Gurion University of Negev Ashkelon Israel"},{"name":"Medicine B Department Barzilai Medical Center Ben Gurion University of Negev Ashkelon Israel"},{"name":"Allergy and Clinical Immunology Unit Barzilai Medical Center Ben Gurion University of Negev Ashkelon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Mishal","sequence":"additional","affiliation":[{"name":"Medicine B Department Barzilai Medical Center Ben Gurion University of Negev Ashkelon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menachem","family":"Schlesinger","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Unit Barzilai Medical Center Ben Gurion University of Negev Ashkelon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp011186"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1972.tb01420.x"},{"key":"e_1_2_5_4_1","first-page":"214","article-title":"Epidemiology of urticaria in Spain","volume":"14","author":"Gaig P","year":"2004","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2010.03840.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03324769"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1179\/acb.2010.039"},{"key":"e_1_2_5_8_1","first-page":"32","article-title":"Urticaria in the elderly","volume":"100","author":"Ramos\u2010Romey C","year":"2008","journal-title":"Bol Asoc Med P R"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02178.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02179.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04582.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.116217"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2007.00276.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02175.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1991.tb03891.x"},{"key":"e_1_2_5_16_1","first-page":"47","article-title":"Coping with pruritus \u2013 a common geriatric complaint","volume":"33","author":"Thorne EG","year":"1978","journal-title":"Geriatrics"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2011.07.012"},{"key":"e_1_2_5_18_1","first-page":"367","article-title":"Mast cell heterogeneity in chronic idiopathic urticaria","volume":"65","author":"Kaufman A","year":"1990","journal-title":"Ann Allergy"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02704.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0307-6938.2001.00962.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550410026939"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70495-0"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.11.040"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000090656"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.12.014"},{"issue":"2","key":"e_1_2_5_26_1","first-page":"21","article-title":"Epidemiology, healthcare, resources, use and clinical features of different types of urticaria","volume":"2","author":"Ferrer M","year":"2009","journal-title":"J Investig Allergol Clin Immunol"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.12109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.12109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T19:26:06Z","timestamp":1696274766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.12109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,8]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/ijd.12109"],"URL":"https:\/\/doi.org\/10.1111\/ijd.12109","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718028330.793480083","asserted-by":"object"}]},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,8]]},"assertion":[{"value":"2013-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}