{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T23:31:00Z","timestamp":1769902260398,"version":"3.49.0"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T00:00:00Z","timestamp":1373241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Many cases of leukotrichia are associated with vitiligo. Hair follicles are believed to be the source of melanocytes for skin repigmentation using standard medical therapy for vitiligo. Vitiliginous areas with overlying leukotrichia usually fail to achieve repigmentation by conventional medical treatments as a result of a deficient melanocyte reservoir. Even after the successful repigmentation of vitiliginous skin by medical therapies, leukotrichia hairs may remain depigmented, causing a major psychological impact to the patient. In such cases, surgical treatments may help to achieve the repigmentation of leukotrichia hairs. Reports of successful repigmentation in leukotrichia using different surgical treatments for vitiligo are few.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study reports the benefit of autologous non\u2010cultured melanocyte\u2010keratinocyte transplantation (<jats:styled-content style=\"fixed-case\">MKT<\/jats:styled-content>) in patients with vitiligo\u2010associated leukotrichia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We report four cases of vitiligo\u2010associated leukotrichia treated with <jats:styled-content style=\"fixed-case\">MKT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All four patients showed significant repigmentation in vitiligo\u2010associated leukotrichia after <jats:styled-content style=\"fixed-case\">MKT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Melanocyte\u2010keratinocyte transplantation may represent a good therapeutic option for the repigmentation of vitiligo\u2010associated leukotrichia. This series includes only four responsive cases. Larger prospective studies are needed to determine the true response rate and mechanism of repigmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12134","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T08:32:51Z","timestamp":1373272371000},"page":"1383-1386","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Repigmentation of vitiligo\u2010associated leukotrichia after autologous, non\u2010cultured melanocyte\u2010keratinocyte transplantation"],"prefix":"10.1111","volume":"52","author":[{"given":"Mohammed I.","family":"Al Jasser","sequence":"first","affiliation":[{"name":"Department of Dermatology and Skin Science University of British Columbia Vancouver BC Canada"},{"name":"Division of Dermatology Department of Medicine King Saud Bin Abdulaziz University for Health Sciences King Fahad National Guard Hospital King Abdulaziz Medical City Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassel","family":"Ghwish","sequence":"additional","affiliation":[{"name":"National Center for Vitiligo and Psoriasis Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Al Issa","sequence":"additional","affiliation":[{"name":"National Center for Vitiligo and Psoriasis Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev V.","family":"Mulekar","sequence":"additional","affiliation":[{"name":"National Center for Vitiligo and Psoriasis Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.32708"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01072.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1995.tb00275.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32210.x"},{"key":"e_1_2_5_6_1","first-page":"252","article-title":"Repigmentation of leukotrichia over vitiligo patches after punch grafting","volume":"64","author":"Malakar S","year":"1998","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1001\/archderm.1992.01680170134031","article-title":"Repigmentation of leukotrichia by epidermal grafting and systemic psoralen plus UV\u2010A","volume":"128","author":"Hann SK","year":"1992","journal-title":"Arch Dermatol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1997.tb02303.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02407.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02226.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01628.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04172.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70121-5"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.12134","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.12134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T23:23:50Z","timestamp":1696289030000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.12134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,8]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/ijd.12134"],"URL":"https:\/\/doi.org\/10.1111\/ijd.12134","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,8]]},"assertion":[{"value":"2013-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}