{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T14:05:30Z","timestamp":1774188330324,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T00:00:00Z","timestamp":1412035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mycetomas are chronic subcutaneous infections caused by either fungi (eumycetomas) or bacteria (actinomycetomas). Eumycetoma is commonly seen in tropical and subtropical climates, usually in males working in occupations prone to trauma. <jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>spergillus<\/jats:italic> spp. are an uncommon cause of mycetomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We describe a patient with eumycetoma attributable to <jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>spergillus nidulans<\/jats:italic> presenting in a sporotrichoid distribution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>A 45\u2010year\u2010old man with type 2 diabetes mellitus and hypertension presented with multiple lumps over the right lower limb of four\u00a0months in duration. He had initially developed a solitary lesion over the right ankle, followed by multiple similar lumps which had spread upwards to involve the right thigh. The entire lower limb was edematous. The patient denied any trauma preceding the symptoms. Biopsy revealed pseudoepitheliomatous hyperplasia with extensive granulomatous infiltrate in the dermis and subcutaneous tissue. Grocott\u2013Gomorri staining revealed fungal elements. Culture on Sabouraud's agar revealed a whitish colony that later turned green. <jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>spergillus nidulans<\/jats:italic> mycetoma in a sporotrichoid distribution was diagnosed. The patient was started on oral itraconazole 200\u00a0mg twice daily, which resulted in complete regression of the lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>Aspergillus<\/jats:italic> spp. have emerged as important opportunistic pathogens, especially in immunosuppressed patients. <jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>spergillus nidulans<\/jats:italic> occurs frequently in soil, decaying vegetation, and water but has very rarely been described as a cause of mycetoma. The infection responds well to treatment with itraconazole, voriconazole, and amphotericin B. The current patient represents the first demonstration of <jats:italic><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>.\u00a0nidulans<\/jats:italic> mycetoma presenting in a sporotrichoid distribution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12571","type":"journal-article","created":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T09:23:59Z","timestamp":1412069039000},"page":"74-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["First reported case of <i>Aspergillus nidulans<\/i> eumycetoma in a sporotrichoid distribution"],"prefix":"10.1111","volume":"54","author":[{"given":"Rajesh","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Dermatology Command Hospital Pune Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biju","family":"Vasudevan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay K.","family":"Sahni","sequence":"additional","affiliation":[{"name":"Department of Microbiology Armed Forces Medical College Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pragasam","family":"Vijendran","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shekhar","family":"Neema","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veena","family":"Kharayat","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01019-06"},{"key":"e_1_2_5_3_1","first-page":"437","article-title":"First case of white grain eumycetoma in Tanzania","volume":"10","author":"Nicolle C","year":"1906","journal-title":"Arch Parasit"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1929.01440050052005"},{"key":"e_1_2_5_5_1","first-page":"359","article-title":"Aspergillus nidulans, agent of mycetoma","volume":"61","author":"Baylet R","year":"1968","journal-title":"Bull Soc Pathol Exot Filiales"},{"key":"e_1_2_5_6_1","first-page":"60","article-title":"Maduromycetoma caused by Aspergillus nidulans","volume":"74","author":"Mahgoub El\u2010S","year":"1971","journal-title":"J Trop Med Hyg"},{"key":"e_1_2_5_7_1","first-page":"41","article-title":"Mycetoma caused by Aspergillus nidulans in India","volume":"88","author":"Joshi KR","year":"1985","journal-title":"J Trop Med Hyg"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.40433"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.9735\/0976-5530.3.7.212-214"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.45110"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.82409"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.2.271"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.12571","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.12571","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.12571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T20:51:28Z","timestamp":1696366288000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.12571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,30]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/ijd.12571"],"URL":"https:\/\/doi.org\/10.1111\/ijd.12571","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,30]]},"assertion":[{"value":"2014-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}