{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T07:46:46Z","timestamp":1724053606265},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T00:00:00Z","timestamp":1416960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intralesional bleomycin is effective for the treatment of various dermatologic conditions. However, the efficacy of intralesional bleomycin for the treatment of corns has not been established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 50 patients with plantar corns were recruited and equally divided between groups A and B. Groups A and B were then treated with intralesional bleomycin (1\u00a0mg\/ml) after paring the hyperkeratotic tissue and simple paring, respectively. The patients visited our clinic at 3\u2010week intervals and were treated for a maximum of 10 sessions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients in groups A and B were treated for 35 and 29 corns, respectively. The curative rates of the patients in groups A and B were 37% (13 of 35) and 7% (three of 29), respectively. The proportions of lesions in groups A and B that demonstrated a decrease in size by &gt;50% were 80% (28 of 35) and 38% (11 of 29), respectively. The total number of patients that demonstrated excellent symptomatic improvement in group A was 15 of 22. Excellent responses were achieved within a small number of treatment sessions, ranging from one to four sessions (average: 2.6). Statistical differences in terms of the degree of size reduction and pain relief were noted between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study provides evidence that intralesional bleomycin (1\u00a0mg\/ml) injection could be one of the ideal treatments for corn. Intralesional bleomycin is particularly useful for reducing lesional pain and size within a short period.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12586","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T14:36:58Z","timestamp":1417012618000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of intralesional bleomycin for the treatment of plantar hard corns"],"prefix":"10.1111","volume":"53","author":[{"given":"Woo Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology The Armed Forces Hongcheon Hospital Hongcheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong Hyun","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Eun","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kee Chan","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,26]]},"reference":[{"key":"e_1_2_4_2_1","volume-title":"Cutaneous Disorders of the Lower Extremity","author":"Dockery GL","year":"1997"},{"key":"e_1_2_4_3_1","first-page":"112","article-title":"Calluses, corns, and shoes","volume":"10","author":"Richards RN","year":"1991","journal-title":"Semin Dermatol"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34281.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07474.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.00978.x"},{"key":"e_1_2_4_7_1","first-page":"2277","article-title":"Corns and calluses resulting from mechanical 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