{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:16:37Z","timestamp":1790111797785,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T00:00:00Z","timestamp":1419811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Latanoprost (\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    ), a prostaglandin F 2alpha (PGF\n                    <jats:sub>2a<\/jats:sub>\n                    ) analogue used in the treatment of glaucoma, was found to induce skin pigmentation in guinea pigs in addition to its known periocular and iridal pigmentation side effects. This study aims to evaluate the efficacy of topical\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    in the induction of skin repigmentation in patients with vitiligo and to compare its potency with narrow band ultraviolet (\n                    <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\n                    ) B (\n                    <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>\n                    ). The result of their combination was also assessed. This study involved 22 patients with bilateral and symmetrical vitiligo lesions, stable for the last three months, divided into three groups: group I, to evaluate\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    vs. placebo; group\n                    <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>\n                    , to evaluate\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    vs.\n                    <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>\n                    ; and group\n                    <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\n                    , to evaluate the effect of their combination. The response to treatment was evaluated by taking photographic records of the treated lesions with follow\u2010up photography every two weeks. After three months, assessment of the degree and extent of repigmentation was performed. Follow\u2010up assessment was done six months after termination of the trial for the persistence of pigmentation, recurrence, or development of any side effects.\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    was found to be better than placebo and comparable with the\n                    <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>\n                    in inducing skin repigmentation. This effect was enhanced by the addition of\n                    <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>\n                    .\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    could be a promising treatment for vitiligo, especially the periocular variant. Its effect on skin repigmentation could be enhanced by\n                    <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>\n                    exposure.\n                  <\/jats:p>","DOI":"10.1111\/ijd.12631","type":"journal-article","created":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T10:51:46Z","timestamp":1419850306000},"page":"587-593","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["The effect of latanoprost on vitiligo: a preliminary comparative study"],"prefix":"10.1111","volume":"54","author":[{"given":"Tag S.","family":"Anbar","sequence":"first","affiliation":[{"name":"Department of Dermatology Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek 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