{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T12:23:11Z","timestamp":1759666991106},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T00:00:00Z","timestamp":1430784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Occupational toxic epidermal necrolysis (<jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content>) related to <jats:italic>Dalbergia cochinchinensis<\/jats:italic> has seldom been reported in the past. Its clinical characteristic needs to be investigated. This study reports eight cases of such disease in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eight patients with occupational <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> admitted from 2003 to 2012 were retrospectively analyzed and compared with 15 patients admitted with <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> caused by drugs as controls. Patients all received combination therapy of corticosteroid and intravenous immunoglobulin. The times for bullous ceasing, tapering of corticosteroid, and total hospitalization were compared between the two groups of patients. <jats:styled-content style=\"fixed-case\">SCORTEN<\/jats:styled-content>, a severity\u2010of\u2010illness scoring system for <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> prognosis, was applied to evaluate clinical outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The three time measurements in occupational <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> were longer than those in control, and the differences were statistically significant (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0023, 0.026, 0.0017), which means the total dose of corticosteroid needed in occupational <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> was higher than that in the control. There were no deaths in the two groups, although expected deaths were 0.612 and 0.836, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Occupational <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> has a longer progression than <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> caused by drugs, and there is more difficulty in its treatment. Clinicians should pay attention to this disease. However, its mechanism and target therapy remain unclear.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12784","type":"journal-article","created":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T09:34:06Z","timestamp":1430818446000},"page":"1435-1441","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Occupational toxic epidermal necrolysis associated with dalbergia cochinchinensis: a retrospective comparative study of eight cases in China"],"prefix":"10.1111","volume":"54","author":[{"given":"Yongsheng","family":"Yang","sequence":"first","affiliation":[{"name":"Affiliated Huashan Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Affiliated Huashan Hospital Fudan University Shanghai 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