{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:52:15Z","timestamp":1787014335921,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T00:00:00Z","timestamp":1444953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n The Quality of Life Evaluation in Epidermolysis Bullosa (Qo\n LEB<\/jats:styled-content>\n ) questionnaire was developed for use in English\u2010speaking individuals.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n The aims of this study were to translate the Qo\n LEB<\/jats:styled-content>\n into Brazilian Portuguese, to culturally adapt it, and to verify its reliability and validity.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The study followed the steps proposed by the World Health Organization, which include: translation; evaluation by a panel of experts and patients; back translation; and linguistic and cultural adaptation. All subjects were examined and assessed using the Qo\n LEB<\/jats:styled-content>\n and the Dermatology Life Quality Index (\n DLQI<\/jats:styled-content>\n ) or the Children's Dermatology Life Quality Index (\n CDLQI<\/jats:styled-content>\n ). Translation and cultural and linguistic adaptation were conducted by 10 patients, three translators, and the bilingual authors.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The population was composed of 40 children (mean age: 8,15 years) and 17 adults (mean age: 33 years). Among the children, eight had epidermolysis bullosa (\n EB<\/jats:styled-content>\n ) simplex (\n EBS<\/jats:styled-content>\n ), one had junctional\n EB<\/jats:styled-content>\n (\n JEB<\/jats:styled-content>\n ), and 31 had dystrophic\n EB<\/jats:styled-content>\n (\n DEB<\/jats:styled-content>\n ). In the adult group, four of the subjects had\n EBS<\/jats:styled-content>\n , one had\n JEB<\/jats:styled-content>\n , and 12 had\n DEB<\/jats:styled-content>\n . Mean \u00b1 standard deviation (\n SD<\/jats:styled-content>\n ) scores on the Qo\n LEB<\/jats:styled-content>\n in children were 10.60 \u00b1 7.13 in\n EBS<\/jats:styled-content>\n subjects, 9.71 \u00b1 7.87 in children with dominant\n DEB<\/jats:styled-content>\n (\n DDEB<\/jats:styled-content>\n ), and 14.25 \u00b1 9.67 in children with recessive\n DEB<\/jats:styled-content>\n (\n RDEB<\/jats:styled-content>\n ). Mean \u00b1\n SD<\/jats:styled-content>\n scores in adults were 12.50 \u00b1 9.95 in\n EBS<\/jats:styled-content>\n subjects, 12.00 \u00b1 5.83 in\n DDEB<\/jats:styled-content>\n subjects, and 20.20 \u00b1 9.21 in\n RDEB<\/jats:styled-content>\n subjects. The Qo\n LEB<\/jats:styled-content>\n \u2010\n BP<\/jats:styled-content>\n (Brazilian Portuguese) showed high internal consistency (Cronbach's \u03b1 = 0.88) and high test\u2013retest reliability (intraclass correlation coefficient: 0.70), confirming the internal consistency and reproducibility of this Portuguese version. There were significant correlations between Qo\n LEB<\/jats:styled-content>\n scores and both\n CDLQI<\/jats:styled-content>\n (Pearson's\n r<\/jats:italic>\n = 0.688,\n P<\/jats:italic>\n < 0.002) and\n DLQI<\/jats:styled-content>\n (Pearson's\n r<\/jats:italic>\n = 0.807,\n P<\/jats:italic>\n < 0.001) scores.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Epidermolysis bullosa has marked impacts on the lives of\n EB<\/jats:styled-content>\n patients and their families, which are strongly correlated with disease severity. The Brazilian Portuguese version of the Qo\n LEB<\/jats:styled-content>\n is validated and can be recommended for use in subsequent studies.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijd.12819","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T18:19:20Z","timestamp":1445019560000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Translation, cross\u2010cultural adaptation and validation of the Quality of Life Evaluation in Epidermolysis Bullosa instrument in Brazilian Portuguese"],"prefix":"10.1111","volume":"55","author":[{"given":"Tania","family":"Cestari","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital de Cl\u00ednicas de Porto Alegre School of Medicine University of Rio Grande do Sul Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa","family":"Prati","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de Cl\u00ednicas de Porto Alegre School of Medicine University of Rio Grande do Sul Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris B.","family":"Menegon","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de Cl\u00ednicas de Porto Alegre School of Medicine University of Rio Grande do Sul Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilda N.","family":"Prado Oliveira","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas de S\u00e3o Paulo School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cec\u00edlia R.","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas de S\u00e3o Paulo School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Dumet","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas de S\u00e3o Paulo School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas de S\u00e3o Paulo School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9d\u00e9e F.","family":"Murrell","sequence":"additional","affiliation":[{"name":"Department of Dermatology St George Hospital School of Medicine University of New South Wales Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2302\/kjm.47.131"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00793.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05601.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.9.1221"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05783.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.01.038"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1996.tb00992.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1992.tb02521.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020880005846"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05419.x"},{"key":"e_1_2_6_12_1","first-page":"270","article-title":"Translation and cultural adaptation to Portuguese of a quality of life questionnaire for patients with melasma","volume":"34","author":"Cestari TF","year":"2006","journal-title":"Med Cutan Ibero Lat Am"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07591.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.01.049"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16953.x"},{"key":"e_1_2_6_16_1","unstructured":"WeberMB BarzenskiB MazzottiNG et al.Tradu\u00e7\u00e3o e adequa\u00e7\u00e3o cultural para o portugu\u00eas de question\u00e1rios sobre qualidade de vida para pacientes portadores de dermatite at\u00f3pica. 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