{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:50:46Z","timestamp":1791348646959,"version":"4.3.1"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T00:00:00Z","timestamp":1444953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Povidone\u2013iodine solution is an antiseptic that is used worldwide as surgical paint and is considered to have a low irritant potential. Post\u2010surgical severe irritant dermatitis has been described after the misuse of this antiseptic in the surgical setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2011 and June 2013, 27 consecutive patients with post\u2010surgical contact dermatitis localized outside of the surgical incision area were evaluated. Thirteen patients were also available for patch testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients developed dermatitis the day after the surgical procedure. Povidone\u2010iodine solution was the only liquid in contact with the skin of our patients. Most typical lesions were distributed in a double lumbar parallel pattern, but they were also found in a random pattern or in areas where a protective pad or an occlusive medical device was glued to the skin. The patch test results with povidone\u2010iodine were negative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Povidone\u2010iodine\u2013induced post\u2010surgical dermatitis may be a severe complication after prolonged surgical procedures. As stated in the literature and based on the observation that povidone\u2010iodine\u2013induced contact irritant dermatitis occurred in areas of pooling or occlusion, we speculate that povidone\u2010iodine together with occlusion were the causes of the dermatitis epidemic that occurred in our surgical setting. Povidone\u2010iodine dermatitis is a problem that is easily preventable through the implementation of minimal routine changes to adequately dry the solution in contact with the skin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12957","type":"journal-article","created":{"date-parts":[[2015,10,17]],"date-time":"2015-10-17T03:22:31Z","timestamp":1445052151000},"page":"540-545","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Povidone\u2010iodine induced post\u2010surgical irritant contact dermatitis localized outside of the surgical incision area. Report of 27 cases and a literature review"],"prefix":"10.1111","volume":"55","author":[{"given":"Leopoldo","family":"Borrego","sequence":"first","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Universitario Insular Universidad de Las Palmas de Gran Canaria Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noelia","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Universitario Insular Universidad de Las Palmas de Gran Canaria Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaida","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Universitario Insular Universidad de Las Palmas de Gran Canaria Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeray","family":"Pe\u00f1ate","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Universitario Insular Universidad de Las Palmas de Gran Canaria Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000232390"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00499.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000057736"},{"key":"e_1_2_5_5_1","first-page":"414","article-title":"Chemical burn from povidone\u2010iodine: case and review","volume":"10","author":"Rees A","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)80129-X"},{"key":"e_1_2_5_7_1","first-page":"300","article-title":"Alegre de Miquel V. 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