{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:14:33Z","timestamp":1770275673900,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,10,24]],"date-time":"2015-10-24T00:00:00Z","timestamp":1445644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Individuals with psoriasis show conflicting responses to the tuberculin skin test (<jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>), a commonly used screening test for latent tuberculosis infection. An alternative to <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> is <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uanti<jats:styled-content style=\"fixed-case\">FERON<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TB G<\/jats:styled-content>old <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>n\u2010<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ube test (<jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content>), an <jats:italic>in vitro<\/jats:italic> interferon\u2010gamma release assay. This study aimed to determine the effect of the clinical properties of psoriasis (disease severity and koebnerization status) on <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> results and the agreement between the <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content> results in psoriatic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred patients with mild to severe psoriasis were enrolled in this prospective cross\u2010sectional study. Psoriasis properties, including disease severity (psoriasis area and severity index score and koebnerization status), latent tuberculosis infection risk factors, and bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin vaccination history, were recorded. All patients underwent a <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> positivity cut\u2010off point was \u226510 mm for bacillus <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>almette\u2013<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>u\u00e9rin\u2010vaccinated patients and \u22655 mm for non\u2010vaccinated patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Psoriasis area and severity index scores and koebnerization status did not correlate with <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> diameters. Only one of the 23 koebnerization\u2010positive patients developed koebnerization in response to <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content> positivity was prominently higher in the <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>\u2010positive group, and this was the only factor that differed between the <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>\u2010positive and <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>\u2010negative groups (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tuberculin skin test results were not affected by psoriasis severity or koebnerization status. <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content> positivity was prominently higher in the <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>\u2010positive group (<jats:italic>P<\/jats:italic> &lt; 0.001). Overall agreement between <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">GIT<\/jats:styled-content> results was moderate (\u03ba = 0.413). Concurrent negativity (44%) was higher than concurrent positivity (27%).<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.12973","type":"journal-article","created":{"date-parts":[[2015,10,24]],"date-time":"2015-10-24T09:47:05Z","timestamp":1445680025000},"page":"629-633","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association of clinical properties and compatibility of the <scp>Q<\/scp>uanti<scp>FERON<\/scp>\u2010<scp>TB G<\/scp>old <scp>I<\/scp>n\u2010<scp>T<\/scp>ube test with the tuberculin skin test in patients with psoriasis"],"prefix":"10.1111","volume":"55","author":[{"given":"Arzu","family":"Karata\u015f To\u011fral","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Ankara Education and Training Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zg\u00fcl","family":"Mu\u015ftu 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