{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:25:18Z","timestamp":1768454718449,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T00:00:00Z","timestamp":1451347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Folliculotropic mycosis fungoides (<jats:styled-content style=\"fixed-case\">FMF<\/jats:styled-content>) is a rare variant of mycosis fungoides with clinical peculiarities, refractoriness to conventional treatments, and worse prognosis when compared to classic mycosis fungoides.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the clinical and epidemiological characteristics of <jats:styled-content style=\"fixed-case\">FMF<\/jats:styled-content> patients in a single center in Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were retrospectively collected from patients with <jats:styled-content style=\"fixed-case\">FMF<\/jats:styled-content> who attended the Cutaneous Lymphoma Clinic, University of S\u00e3o Paulo Medical School, between 1987 and 2013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010three patients were included (median age 46 years old at diagnosis; 20 male; 27 white). The median disease duration before diagnosis was 3 years. Regarding stage at diagnosis, 61% had advanced stage disease (\u2265<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>b). Follicular papules were reported in 66% and alopecia in 59% of the cases. The most involved regions were limbs, followed by trunk and head. Pruritus was present in 81% of the patients. The median time of patients\u2019 follow\u2010up was 38 months. At the last follow\u2010up visit, 67% of the patients were alive with active disease, 27% deceased, and 6% were in complete remission. Four patients had large cell transformation. At the time of diagnosis, 25% of the patients showed eosinophilia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>Retrospective study with partial unavailable data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The characteristics of our patients with <jats:styled-content style=\"fixed-case\">FMF<\/jats:styled-content> correlated with aspects previously described in the literature, which were at a more advanced stage at diagnosis and had a less favorable outcome. Pruritus is a very common complaint. Large cell transformation should be monitored as it is implicated in poor prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13149","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T08:40:38Z","timestamp":1451378438000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Folliculotropic mycosis fungoides: clinical and epidemiological evaluation in a single center in Brazil"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1154-7186","authenticated-orcid":false,"given":"Janyana M. 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