{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:35:13Z","timestamp":1780695313379,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data were derived from a 15\u2010year retrospective review of electronic records from a large dermatopathology laboratory located in the mid\u2010Atlantic region of the\n                      <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>\n                      . Numbers of diagnoses per month and \u201cper season\u201d were determined. Pairwise comparisons of seasonal data were made using two\u2010sample\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests with significance set at\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Perniosis (chilblains) was significantly more common in winter and spring (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001). Hand, foot, and mouth disease was statistically more prevalent in summer and autumn (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.028). Erythema multiforme was most common in spring and summer (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.004). Grover's disease was most common in winter and spring (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.000039). Guttate psoriasis was non\u2010significantly more common in winter and spring (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.076). No statistically significant seasonal variation was found for erythema dyschromicum perstans (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.899), pityriasis rosea (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.727), or pityriasis lichenoides (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.366).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study found statistically significant seasonal trends for several dermatologic conditions. The study was primarily epidemiologic and was not intended to address histopathologic differences that might underlie the seasonal variations observed. However, further investigation of seasonal differences in the histopathology of erythema multiforme may prove interesting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.13229","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T13:45:25Z","timestamp":1460295925000},"page":"1115-1118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15\u2010year analysis of dermatopathologic data"],"prefix":"10.1111","volume":"55","author":[{"given":"Jeff D.","family":"Harvell","sequence":"first","affiliation":[{"name":"Bethesda Dermatopathology Laboratory Silver Spring MD USA"},{"name":"Department of Dermatology George Washington University School of Medicine Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel 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