{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:32:32Z","timestamp":1760189552414},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cutaneous lymphomas are a heterogeneous group of tumors with various clinical manifestations, histological features, and prognoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among 425 cases of cutaneous lymphoma, we describe eight cases of peripheral T\u2010cell lymphoma, unspecified, presenting with generalized benign\u2010looking dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our case series included eight cases of secondary cutaneous peripheral T\u2010cell lymphoma, unspecified. The observed clinical morphology features included drug eruption\u2010like generalized morbilliform maculopatches in two cases, generalized folliculitis\u2010like papules in two cases, and generalized eczematous dermatitis\u2010like papules and patches in four cases. Histopathological examination demonstrated tumor cell infiltrates of mainly atypical, small\u2010to\u2010medium lymphoid cells that were perivascularly or periadnexally distributed throughout the dermis. Immunohistochemical staining results for <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>2, <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>3, <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4, and <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>8 revealed that the tumor cells were T\u2010cells.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This collection of cases and literature review emphasizes the need for clinical suspicion of peripheral T\u2010cell lymphoma, unspecified, in the differential diagnosis of adult patients with refractory eczematous or benign\u2010looking skin lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13493","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T06:26:46Z","timestamp":1488176806000},"page":"617-622","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Secondary cutaneous peripheral T\u2010cell lymphoma, unspecified, with generalized benign\u2010looking dermatitis: a possibly distinct peripheral T\u2010cell lymphoma"],"prefix":"10.1111","volume":"56","author":[{"given":"Woo Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Ji","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul 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