{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:23:40Z","timestamp":1782440620647,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adult T\u2010cell leukemia\/lymphoma (<jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content>) is an aggressive neoplasm of T\u2010lymphocytes associated with human T\u2010lymphotropic virus type I (<jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101) infection. As <jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101 is endemic in native ethnics in South America, and its infection leads to several chronic diseases as <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> with poor prognosis, we aimed to present three <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> cases and to review current literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case reports<\/jats:title><jats:p>Two cases were from the mountains of Peru, while one was from an endemic harbor of the country. An acute <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> patient presented with multipapular infiltration of the skin and died 2 weeks after admission because of septic shock. The two chronic <jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> patients presented with erythematous plaques and erythroderma. They had swollen lymph nodes, lymphocytosis, and atypical lymphocytes on blood smear, with normal biochemical results. They both passed away a few months after diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Comments<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">ATLL<\/jats:styled-content> is developed after years of <jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101 carrier status; therefore, physicians should know the principal clinical and laboratory findings in order to make prompt diagnosis. Prognosis is still poor in aggressive and indolent variants, with survival rates from months to a few years. Treatment based on chemotherapy, antiretroviral, and allogeneic stem cell transplantation are improving survival rates but with limited results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13567","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T09:22:43Z","timestamp":1488446563000},"page":"503-509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Adult T\u2010cell leukemia\/lymphoma in a Peruvian hospital in human T\u2010lymphotropic virus type 1 (<scp>HTLV<\/scp>\u20101) positive patients"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9413-2439","authenticated-orcid":false,"given":"Milton Jos\u00e9 Max","family":"Rodr\u00edguez\u2010Z\u00fa\u00f1iga","sequence":"first","affiliation":[{"name":"Dermatology Department Hospital Nacional Daniel Alcides Carrion Callao Peru"},{"name":"Universidad Nacional Mayor de San Marcos Lima 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