{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:24:40Z","timestamp":1790699080696,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ratchadapiseksompotch Fund"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The high prevalence of acne vulgaris in teenagers has increased comorbidities. Lasers offer alternative options for acne treatment because they have rapid action, low systemic adverse effects, and do not require everyday treatment. To study the efficacy and patients\u2019 satisfaction of 595\u2010nm pulse dye laser (<jats:styled-content style=\"fixed-case\">PDL<\/jats:styled-content>) treatment of acne vulgaris and acne erythema in adolescents and early adulthood, we designed a blocked\u2010randomized, split\u2010faced 595\u2010nm <jats:styled-content style=\"fixed-case\">PDL<\/jats:styled-content> (fluence 8 J\/cm<jats:sup>3<\/jats:sup> pulse duration 10 ms, spot size 7 mm, 2 session every 2 weeks) study in patients with mild to moderate acne by comparing the laser\u2010treated and non\u2010treated side. The acne lesion counts, acne erythema grading, and acne severity grading were evaluated at baseline and 2, 4, and 8 weeks. Thirty patients were recruited. The results showed no statistically significant difference except the papule count at week 4 which was \u22121.828 on the treated side and 0.103 on the non\u2010treated side of the face, <jats:italic>P<\/jats:italic>\u2010value 0.0018. There was no statistically significant difference of acne severity grading and acne erythema grading between both sides of the face. The mean scores of patients\u2019 satisfaction on the laser\u2010treated side were 75, 81, and 81%, respectively. The <jats:styled-content style=\"fixed-case\">PDL<\/jats:styled-content> treatment in this study reveals no significant improvement in acne therapy; however, the patients were satisfied with this laser treatment.<\/jats:p>","DOI":"10.1111\/ijd.13631","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T04:29:19Z","timestamp":1493267359000},"page":"884-888","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Randomized, controlled trial split\u2010faced study of 595\u2010nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood"],"prefix":"10.1111","volume":"56","author":[{"given":"Ramrada","family":"Lekwuttikarn","sequence":"first","affiliation":[{"name":"Department of Pediatrics Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therdpong","family":"Tempark","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susheera","family":"Chatproedprai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriwan","family":"Wananukul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0490B"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f2634"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2011.07.003"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.5070\/D34HP8N68P"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13191"},{"key":"e_1_2_5_7_1","unstructured":"Clinical practice guideline for acne 2011 [Internet].2011. 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