{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:33:22Z","timestamp":1790084002098,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,4,23]],"date-time":"2017-04-23T00:00:00Z","timestamp":1492905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Burning mouth syndrome (<jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>) is a disorder characterized by chronic mouth pain in the absence of objective clinical abnormalities. Vitamin or mineral deficiencies may have a role in <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>, but data regarding the prevalence and relevance of hematinic deficiencies are conflicting. We aimed to determine the frequency of specific laboratory abnormalities in patients with <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed the results of screening blood tests in patients with <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content> at our institution between January 2003 and December 2013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 659 patients with <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>, the most common decreased values or deficiencies were vitamin D<jats:sub>3<\/jats:sub> (15%), vitamin B<jats:sub>2<\/jats:sub> (15%), vitamin B<jats:sub>6<\/jats:sub> (5.7%), zinc (5.7%), vitamin B<jats:sub>1<\/jats:sub> (5.3%), thyrotropin (<jats:styled-content style=\"fixed-case\">TSH<\/jats:styled-content>) (3.2%), vitamin B<jats:sub>12<\/jats:sub> (0.8%), and folic acid (0.7%). Laboratory values for fasting blood glucose and <jats:styled-content style=\"fixed-case\">TSH<\/jats:styled-content> were increased in 23.7% and 5.2%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with symptoms of <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>, our results suggest it is reasonable to screen for fasting blood glucose, vitamin D (D<jats:sub>2<\/jats:sub> and D<jats:sub>3<\/jats:sub>), vitamin B<jats:sub>6<\/jats:sub>, zinc, vitamin B<jats:sub>1<\/jats:sub>, and <jats:styled-content style=\"fixed-case\">TSH<\/jats:styled-content>. Deficiencies of vitamin B<jats:sub>12<\/jats:sub> and folic acid were rare (&lt;1% abnormal).<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13634","type":"journal-article","created":{"date-parts":[[2017,4,24]],"date-time":"2017-04-24T04:33:19Z","timestamp":1493008399000},"page":"952-956","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Burning mouth syndrome: results of screening tests for vitamin and mineral deficiencies, thyroid hormone, and glucose levels\u2014experience at Mayo Clinic over a decade"],"prefix":"10.1111","volume":"56","author":[{"given":"Claudia S.","family":"Morr Verenzuela","sequence":"first","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D. 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