{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T01:24:30Z","timestamp":1778808270040,"version":"3.51.4"},"reference-count":58,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T00:00:00Z","timestamp":1499040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which fungal species were commonly associated with these mycoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a meta\u2010analysis after a systematic review of the published literature in PubMed, LILACS, and SciELO to estimate the burden of subcutaneous mycoses in 25 regions in Peru. The disease burden was determined in terms of prevalence (number of cases per 100,000 inhabitants) and the number of reported cases per year per region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 26 studies were eligible for inclusion. Results showed that sporotrichosis was the most common subcutaneous mycosis (99.7%), whereas lobomycosis, chromoblastomycosis, and subcutaneous phaeohyphomycosis were rare. Cases of eumycetoma and subcutaneous zygomycosis were not found. Of the 25 regions, the burden of sporotrichosis was estimated for four regions classified as endemic; in nine regions, only isolated cases were reported. The highest burden of sporotrichosis was in Apurimac (15 cases\/100,000 inhabitants; 57 cases\/year), followed by Cajamarca (3\/100,000 inhabitants; 30\/year), Cusco (0.5\/100,000 inhabitants; 4\/year), and La Libertad (0.2\/100,000 inhabitants; 2\/year). In two regions, the mycoses predominantly affected children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sporotrichosis is the most common subcutaneous mycosis in Peru, with a high disease burden in Apurimac. Chromoblastomycosis, lobomycosis, and subcutaneous phaeohyphomycosis are rare mycoses in Peru.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13665","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T05:12:37Z","timestamp":1499058757000},"page":"1037-1045","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Subcutaneous mycoses in Peru: a systematic review and meta\u2010analysis for the burden of disease"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0471-6746","authenticated-orcid":false,"given":"Max Carlos","family":"Ram\u00edrez Soto","sequence":"first","affiliation":[{"name":"Medicine School Universidad Nacional Mayor de San Marcos Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"German","family":"Malaga","sequence":"additional","affiliation":[{"name":"Medicine School Universidad Peruana Cayetano Heredia Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,3]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"127","volume-title":"Micologia M\u00e9dica Ilustrada","author":"Arenas R","year":"2008"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.539631"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.10.883"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-012-0275-3"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myu062"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002550"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2012.10.001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2006.05.007"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652015000700009"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40949"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qco.0000216625.28692.67"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.02937.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S46251"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/15.4.639"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.2.236"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1086\/345437"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127924"},{"key":"e_1_2_5_19_1","first-page":"121","article-title":"[Clinical and epidemiological profile of sporotrichosis in a reference clinic at Abancay, Peru: 2004\u20132011]","volume":"16","author":"Ramirez Soto MC","year":"2012","journal-title":"Rev Peru Epidemiol"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1086\/313607"},{"key":"e_1_2_5_21_1","first-page":"87","article-title":"[Cutaneous sporotrichosis in Hospital Regional of Cajamarca]","volume":"11","author":"Garc\u00eda M","year":"2011","journal-title":"Dermatol Peru"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02141284"},{"key":"e_1_2_5_23_1","first-page":"59","article-title":"Esporotricosis en la altura de Cusco\u2010Per\u00fa nueva zona end\u00e9mica. experiencia de once a\u00f1os","volume":"9","author":"Garc\u00eda R","year":"1998","journal-title":"Folia Dermatol Peru"},{"key":"e_1_2_5_24_1","first-page":"28","article-title":"[Chromoblastomycosis by Clasdospirum sp.]","volume":"15","author":"Cavero J","year":"2004","journal-title":"Folia Dermatol Peru"},{"key":"e_1_2_5_25_1","first-page":"63","article-title":"[Jorge Lobo's disease (keloyd blastomycosis). Diagnosis of the first Peruvian case]","volume":"26","author":"Romero RO","year":"1972","journal-title":"Arch Per Pat Clin"},{"key":"e_1_2_5_26_1","first-page":"9","article-title":"[Clinical profile and incidence of palpebral sporotrichosis: 16 new cases]","volume":"17","author":"Miranda H","year":"2006","journal-title":"Folia Dermatol Peru"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.17843\/rpmesp.2014.312.58"},{"key":"e_1_2_5_28_1","unstructured":"Servicio Nacional de Metereolog\u00eda e Hidrologia del Per\u00fa (SENAMHI).Mapa clim\u00e1tico del Per\u00fa[Internet].Lima:SENAMHI;2016[cited 2016 Jun 5]. Available from:http:\/\/www.peruclima.pe\/?p=mapa-climatico-del-peru"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_2_5_30_1","first-page":"104","article-title":"[Cutaneous sporotrichosis in children at Regional Hospital in Peru]","volume":"14","author":"Garc\u00eda M","year":"2004","journal-title":"Dermatol Peru"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02051223"},{"key":"e_1_2_5_32_1","first-page":"5","article-title":"[Sporotrichosis in Abancay, Peru]","volume":"4","author":"Flores A","year":"1991","journal-title":"Rev Peru Epidemiol"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.17843\/rpmesp.2015.321.1593"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/IPC.0b013e31818add36"},{"key":"e_1_2_5_35_1","first-page":"123","article-title":"[Facial sporotrichosis in children: a diagnostic challenge]","volume":"14","author":"Timan\u00e1\u2010Palacios D","year":"2014","journal-title":"Dermatol Peru"},{"key":"e_1_2_5_36_1","first-page":"105","article-title":"[The earliest case of pediatric sporotrichosis in Peru]","volume":"15","author":"Garc\u00eda R","year":"2004","journal-title":"Folia Dermatol Peru"},{"key":"e_1_2_5_37_1","first-page":"580","article-title":"[Sporotrichosis in the middle of the face]","volume":"28","author":"Bartolo L","year":"2013","journal-title":"Piel (Bar)"},{"key":"e_1_2_5_38_1","first-page":"201","article-title":"Jorge Lobo's disease. Second Peruvian case","volume":"13","author":"Talhari S","year":"1985","journal-title":"Med Cutan Ibero Lat Am"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.12-0428"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1726-46342011000300023"},{"key":"e_1_2_5_41_1","first-page":"79","article-title":"[Subcutaneous phaeohyphomycosis]","volume":"21","author":"Vilcahuam\u00e1n V","year":"2010","journal-title":"Folia Dermatol Peru"},{"key":"e_1_2_5_42_1","unstructured":"SegoviaG GarciaV MenesesM et\u00a0al.Abstracts of the 4th Congress International of the National Instituto of Health 11\u201313 November 2010.Lima Peru:4th Congress International of the National Instituto of Health;2010. [Reporte sobre un caso de esporotricosis en la regi\u00f3n Ayacucho]. 43 p."},{"issue":"2","key":"e_1_2_5_43_1","first-page":"105","article-title":"Esporotricosis en la infancia: revisi\u00f3n de 138 casos en una regi\u00f3n andina end\u00e9mica","volume":"62","author":"Aguilera S","year":"2005","journal-title":"An Pediatr (Barc)"},{"key":"e_1_2_5_44_1","unstructured":"MenesesG CabezasC BustamanteB et\u00a0al.Abstracts of the 5th Pan\u2010American Congress of Infectious Diseases 7\u201310 April 1991.Lima Peru:Pan\u2010American Congress of Infectious Diseases;1991. Report of 261 cases of sporotrichosis from 1987 to 1989 Centro Medico Santa Teresa Abancay Peru [abstract VI]."},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00808-07"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02051412"},{"key":"e_1_2_5_47_1","first-page":"147","article-title":"[Sporotrichosis: recent advances in the laboratory diagnosis, histopathology and epidemiology in Mexico]","volume":"59","author":"Carrada T","year":"2012","journal-title":"Rev Latinoamer Patol Clin"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1086\/649891"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2010.01.001"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05849.x"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02051697"},{"key":"e_1_2_5_52_1","first-page":"837","article-title":"[A new case of Jorge Lobo disease in French Guyana]","volume":"76","author":"Pradinaud R","year":"1969","journal-title":"Bull Soc Fr Dermatol Syphiligr"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1996.55.45"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780500543238"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70335-1"},{"key":"e_1_2_5_56_1","unstructured":"Servicio Nacional de Metereolog\u00eda e Hidrolog\u00eda (SENAMHI).Caracterizaci\u00f3n clim\u00e1tica de las regiones Cusco y Apur\u00edmac.Lima:SENAMHI;2012."},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001673"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(99)90173-6"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003110"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13665","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13665","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:13:31Z","timestamp":1695550411000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,3]]},"references-count":58,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/ijd.13665"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13665","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,3]]},"assertion":[{"value":"2016-12-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}