{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T19:27:08Z","timestamp":1749324428601},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T00:00:00Z","timestamp":1497916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>IgE quantitative assaying of allergens (Ig<jats:styled-content style=\"fixed-case\">EQAA<\/jats:styled-content>) has long been implemented by allergists in determining patients\u2019 reactivities for allergic rhinitis and asthma, two of the three diagnoses in atopic syndrome. This test operates by measuring the patient's IgE response to different allergens and can identify potential triggers for a patient's symptoms. Despite this, Ig<jats:styled-content style=\"fixed-case\">EQAA<\/jats:styled-content> has yet to see the same widespread use in the field of dermatology, specifically in the treatment of patients with atopic dermatitis (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The affected body surface area (<jats:styled-content style=\"fixed-case\">BSA<\/jats:styled-content>) at first presentation, Ig<jats:styled-content style=\"fixed-case\">EQAA<\/jats:styled-content> classes, and total immunoglobulin E (IgE) concentration were taken retrospectively for 54 patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 54 patients observed, 41 had an abnormally high total IgE concentration (76%). Additionally, it was observed that nine (17%) of our patients significantly improved after making lifestyle changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Knowledge of the identified specific antigens can guide patients to make lifestyle modifications that may improve disease outcomes. Ig<jats:styled-content style=\"fixed-case\">EQAA<\/jats:styled-content> and avoidance of allergens may help some patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13673","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T10:23:04Z","timestamp":1497954184000},"page":"1150-1153","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Identification of allergens by IgE\u2010specific testing improves outcomes in atopic dermatitis"],"prefix":"10.1111","volume":"56","author":[{"given":"Brett M.","family":"Will","sequence":"first","affiliation":[{"name":"Georgetown University School of Biomedical Graduate Education Washington, DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Severino","sequence":"additional","affiliation":[{"name":"Biostatistician The Queen's Medical Center Honolulu, HI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"University of Hawaii School of Medicine Department of Medicine Honolulu, HI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1992.tb00191.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.11-RA-0371"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2013.11.002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1986.tb00773.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01916.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017520"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1982.tb02318.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-0492"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.115569"},{"key":"e_1_2_6_11_1","first-page":"318","article-title":"Determination of IgE antibodies to Candida albicans mannan with nitrocellulose\u2010RAST in patients with atopic diseases","volume":"24","author":"Nermes M","year":"1994","journal-title":"Clin Exp Dermatol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1989.tb02390.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690110059007"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T12:46:56Z","timestamp":1695991616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,20]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/ijd.13673"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13673","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,20]]},"assertion":[{"value":"2015-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}