{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:29:03Z","timestamp":1789172943091,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T00:00:00Z","timestamp":1498521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Onychomycosis is a fungal nail infection caused primarily by dermatophytes. Several other nail disorders, including psoriasis, can simulate onychomycosis. Accurate diagnosis is therefore vital for the ongoing treatment and management of onychomycosis and to avoid misdiagnosis and treatment delay, which can be both lengthy and costly. Often, a combination of histologic and laboratory techniques is used to obtain an accurate diagnosis. The potential diagnostic challenges associated with the differential diagnosis of onychomycosis caused by dermatophytes and the most common techniques used to confirm the diagnosis are discussed.<\/jats:p>","DOI":"10.1111\/ijd.13690","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T09:59:15Z","timestamp":1498557555000},"page":"131-138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Examining the importance of laboratory and diagnostic testing when treating and diagnosing onychomycosis"],"prefix":"10.1111","volume":"57","author":[{"given":"Mahmoud","family":"Ghannoum","sequence":"first","affiliation":[{"name":"Case Western University Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranab","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Case Western University Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Isham","sequence":"additional","affiliation":[{"name":"Case Western University Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Markinson","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Del","family":"Rosso","sequence":"additional","affiliation":[{"name":"Touro University Nevada Henderson NV USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Leal","sequence":"additional","affiliation":[{"name":"PharmaDerm a division of Fougera Pharmaceuticals Inc. Princeton NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,27]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"762","article-title":"Onychomycosis: current trends in diagnosis and treatment","volume":"88","author":"Westerberg DP","year":"2013","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2009.01107.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000358586"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.149.s65.5.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.11.3.415"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2007.01422.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.2.305"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2012.697990"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-006-1156-1"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpm.2004.06.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00667.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.32753"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12593"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2013.06.009"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)01480-4"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.8.2.240"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.990080412"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0732-8893(90)90027-S"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1992.tb00276.x"},{"key":"e_1_2_9_21_1","first-page":"407","article-title":"The cost effectiveness of testing for onychomycosis versus empiric treatment of onychodystrophies with oral antifungal agents","volume":"64","author":"Mehregan DR","year":"1999","journal-title":"Cutis"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03704.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.03.033"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00890.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1994.tb00781.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1998.00517.x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1439-0507.2009.01771.x","article-title":"Direct detection of five common dermatophyte species in clinical samples using a rapid and sensitive 24\u2010h PCR\u2010ELISA technique open to protocol transfer","volume":"54","author":"Beifuss B","year":"2009","journal-title":"Mycoses"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08100.x"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2008.02036.x"},{"key":"e_1_2_9_30_1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1128\/CMR.00072-12","article-title":"Matirx\u2010Assisted laser Desorption Ionization\u2010Time of Flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology","volume":"2","author":"Clark AE","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"e_1_2_9_31_1","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1128\/JCM.01280-11","article-title":"Dermatophyte identification using matrix\u2010assisted laser desorption ionization\u2013time of flight mass spectrometry","volume":"2011","author":"Theel ES","year":"2011","journal-title":"J Clin Microbiol"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06634-11"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2012.685186"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32834f5f6e"},{"key":"e_1_2_9_35_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.5826\/dpc.0502a05","article-title":"Dermoscopic patterns in patients with a clinical diagnosis of onychomycosis\u2010results of a prospective study including data of potassium hydroxide (KOH) and culture examination","volume":"5","author":"Jesus\u2010Silva MA","year":"2015","journal-title":"Dermatol Pract and Concept."},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.04.010"},{"key":"e_1_2_9_37_1","first-page":"702","article-title":"Diagnosis and management of tinea infections","volume":"90","author":"Ely JW","year":"2014","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_38_1","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/jamadermatol.2015.4190","article-title":"Cost\u2010effectiveness of confirmatory testing before treatment of onychomycosis","volume":"152","author":"Mikailov A","year":"2015","journal-title":"JAMA Dermatology"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7190.1031"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1992.tb00110.x"},{"key":"e_1_2_9_41_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000443773","article-title":"Successful treatment of Paecilomyces lilacinus onychomycosis with efinaconazole and Tavaborole","volume":"1","author":"Evans JM","year":"2015","journal-title":"Skin Appendage Disorders."},{"key":"e_1_2_9_42_1","volume-title":"Dako Education Guide: Special Stains and H & E","author":"Kumar GL","year":"2010"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T03:18:59Z","timestamp":1695957539000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,27]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/ijd.13690"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13690","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,27]]},"assertion":[{"value":"2017-01-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}