{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:06:27Z","timestamp":1787238387614,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T00:00:00Z","timestamp":1503360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Clinical and dermoscopic features of Bowen's disease (\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      ) show great diversity. Some lesions of\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      are often difficult to be differentiated from seborrheic keratosis, actinic keratosis, lichen planus\u2010like keratosis, etc. It is necessary to fully describe the dermoscopic features of the disease, considering differential diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the dermoscopic feautres of Bowen's disease and summarize the dermoscopic differential diagnosis of the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>Altogether 146 lesions with a histopathological diagnosis of Bowen's disease were consecutively included in this study. All the lesions were imaged with dermoscopy and analyzed for dermoscopic features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 146 lesions were analyzed. The dermoscopic features most frequently observed in our series of lesions were scales (78.8%), glomerular vessels (69.2%), yellow crusts (56.8%), focal hemorrhage (55.5%), focal\/multifocal hypopigmentation (44.5%), and linear irregular vessels (42.5%). Besides, we found two new dermoscopic signs in\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      : the double\u2010edge sign (30.1%) and the clusters of brown structureless areas (38.4%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Bowen's disease presents a variety of dermoscopic features. The recognition of two new dermoscopic signs of\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      and fully understanding its dermoscopic features will help us in differential diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.13734","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:42:45Z","timestamp":1503448965000},"page":"1022-1025","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["What's new in dermoscopy of Bowen's disease: two new dermoscopic signs and its differential diagnosis"],"prefix":"10.1111","volume":"56","author":[{"given":"Yi","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Dermatology the 1st Affiliated Hospital of Dalian Medical University Dalian 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