{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T17:07:53Z","timestamp":1747674473396},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T00:00:00Z","timestamp":1506470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mucocutaneous manifestations are one of the first clinical signs in patients infected with human immunodeficiency virus (<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>). To the best of our knowledge, there has been no previous study describing dermatologic manifestations in Mauritanians infected with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>. The aim of the present study was to determine the profiles of mucocutaneous manifestations in relation to <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content><jats:sub>4<\/jats:sub> T cell count in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive Mauritanian patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 86 adult patients aged &gt; 18 years old attending the Ambulatory Treatment Center of the National Hospital of Nouakchott, Mauritania, with newly diagnosed <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and who were not under antiretroviral treatment were included in the study in 2015. Dermatologic manifestations were documented before initiating antiretroviral treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most of the included patients were in clinical stage 3 of the World Health Organization classification at initial diagnosis, with the mean <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content><jats:sub>4<\/jats:sub> T cell count (\u00b1 <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) of 514 \u00b1 319 cells\/mm<jats:sup>3<\/jats:sup> (range, 2\u20131328 cells\/mm<jats:sup>3<\/jats:sup>), and 19 of 86 (22.1%) patients had <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content><jats:sub>4<\/jats:sub> T cell counts below 200 cells\/mm<jats:sup>3<\/jats:sup>. More than half (64%) of newly diagnosed <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients had dermatoses, including the following: pruritic papular eruption (44.2%), seborrheic dermatitis (4.7%), Kaposi's sarcoma (3.5%), extensive xerosis cutis (2.3%), drug\u2010induced skin reactions (1.2%), and various infectious dermatoses (dermatophyte infections [16.3%], oral candidiasis [11.6%], herpes zoster [8.1%], and scabies [2.3%]). A low <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content><jats:sub>4<\/jats:sub> T cell count (&lt; 200 cells\/mm<jats:sup>3<\/jats:sup>) was significantly correlated (<jats:italic>P<\/jats:italic> &lt; 0.05) with the presence of following dermatoses: dermatophytosis, oral candidiasis, Kaposi's sarcoma, seborrheic dermatitis, and extensive xerosis cutis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mucocutaneous lesions occur throughout the course of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection, and dermatologic findings in Mauritanian <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients are similar to those of patients in other countries. Early detection of skin disorders in some patients may help establish the diagnosis of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and management of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010associated diseases, limiting the cost of care in low\u2010resource countries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13737","type":"journal-article","created":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T07:42:11Z","timestamp":1506498131000},"page":"1421-1424","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Mucocutaneous manifestations in human immunodeficiency virus (HIV)\u2010infected patients in Nouakchott, Mauritania"],"prefix":"10.1111","volume":"56","author":[{"given":"Boushab M.","family":"Boushab","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Infectious Diseases Kiffa Regional Hospital Assaba Mauritania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatim\u2010Zahra","family":"Malick Fall","sequence":"additional","affiliation":[{"name":"School of Medicine National Institute of Hepatology\u2010Virology in Nouakchott Nouakchott Mauritania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taleb K.","family":"Ould Cheikh Mohamed Vadel","sequence":"additional","affiliation":[{"name":"Outpatient Department Hospital Center of Nouakchott Nouakchott Mauritania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed L.","family":"Ould Cheikh Mela\u00efnine","sequence":"additional","affiliation":[{"name":"Outpatient Department Hospital Center of Nouakchott Nouakchott Mauritania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed V.","family":"Maazouz","sequence":"additional","affiliation":[{"name":"Outpatient Department Hospital Center of Nouakchott Nouakchott 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