{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:34:27Z","timestamp":1778628867298,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T00:00:00Z","timestamp":1505692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pitted keratolysis (<jats:styled-content style=\"fixed-case\">PK<\/jats:styled-content>) is a common bacterial infection of skin characterized by noninflammatory superficial pits. Very few studies have focused on variations in clinical manifestations of <jats:styled-content style=\"fixed-case\">PK<\/jats:styled-content>. We conducted this study so that diagnosis of this treatable condition is not missed when it presents in an uncommonly perceived way.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims and objectives<\/jats:title><jats:p>Assessment of <jats:styled-content style=\"fixed-case\">PK<\/jats:styled-content> patients for various sites and morphologies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A total of 30 patients with <jats:styled-content style=\"fixed-case\">PK<\/jats:styled-content> were assessed for various sites and morphologies. Bacterial and fungal cultures along with histopathology were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 30 patients, 24 were females. Hyperhidrosis and malodour were the most common symptoms. Interdigital interface skin of the toes was the first site affected in most patients. Plantar skin was affected in all patients with involvement of interface skin of the toes in 29 patients. Other sites affected were palms, finger web spaces, nonglabrous skin, paronychium, and nail. Other than classical pits, scaly crusted inflammatory lesions with post\u2010inflammatory hyperpigmentation (<jats:styled-content style=\"fixed-case\">PIH<\/jats:styled-content>) were noted. Associated keratoderma was also reported in some patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The presence of hyperhidrosis, malodour, and plantar lesions is consistent with previous studies. Interface skin between toes as the first site affected, involvement of toe web spaces, and associated keratoderma have been reported rarely. However, female preponderance, involvement of finger web spaces, nonglabrous skin, paronychium, nail changes, the presence of inflammation with crusting, and <jats:styled-content style=\"fixed-case\">PIH<\/jats:styled-content> have never been reported previously.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PK<\/jats:styled-content> can involve web spaces, nonglabrous skin, and paronychium, and can cause nail changes. The lesions can be inflammatory with crusting and <jats:styled-content style=\"fixed-case\">PIH<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13744","type":"journal-article","created":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T04:58:39Z","timestamp":1505797119000},"page":"1154-1160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Pitted keratolysis \u2013 a study of various clinical manifestations"],"prefix":"10.1111","volume":"56","author":[{"given":"Meena","family":"Makhecha","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shreya","family":"Dass","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tishya","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riddhi","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tulika","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipali","family":"Rathod","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology H.B.T. Medical College and Dr. R.N. Cooper Hospital Mumbai Maharashtra India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1001\/archderm.1987.01660340082025","article-title":"Pitted keratolysis. The role of Micrococcus sedentarius","volume":"123","author":"Nordstrom KM","year":"1987","journal-title":"Arch Dermatol"},{"key":"e_1_2_7_3_1","first-page":"1","article-title":"Pitted keratolysis","volume":"11","author":"English JC","year":"2003","journal-title":"eMedicine J"},{"key":"e_1_2_7_4_1","first-page":"10","article-title":"Keratoma plantare sulcatum","volume":"7","author":"Castellani A","year":"1910","journal-title":"J Ceylon Brit Med Assoc"},{"key":"e_1_2_7_5_1","first-page":"61","article-title":"Keratolysis plantare sulcatum, lesions due to an actinomycotic fungus","volume":"65","author":"Acton HW","year":"1930","journal-title":"Indian Med Gazette"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1965.01600140039008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.16250"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1979.tb00302.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.31922"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.18211899.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.182351"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00035.x"},{"key":"e_1_2_7_13_1","first-page":"157","article-title":"Pitted keratolysis of hyperkeratotic form and isolation of the etiologic agent: Corynebacterium sp","volume":"15","author":"Conti D\u00edaz IA","year":"1987","journal-title":"Med Cutan Ibero Lat Am"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2012.e4"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-016-2223-y"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T12:47:02Z","timestamp":1695991622000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,18]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/ijd.13744"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13744","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,18]]},"assertion":[{"value":"2016-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}