{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:40:31Z","timestamp":1770882031369,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T00:00:00Z","timestamp":1509408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Becker's nevus (BN<\/jats:styled-content>) presents as a hairy patch or plaque with or without proliferation of the dermal smooth muscles. BN<\/jats:styled-content> has been described as acquired as found in a similar entity, congenital smooth muscle hamartoma (CSMH<\/jats:styled-content>). This study was aimed at evaluating the clinicopathological aspects of BN<\/jats:styled-content> in Korean cases in differential diagnosis with CSMH<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>We performed a retrospective study of 103 patients histopathologically diagnosed as having BN<\/jats:styled-content> or CSMH<\/jats:styled-content>. The cases included 40 cases diagnosed with BN<\/jats:styled-content> or CSMH<\/jats:styled-content> before the age of 10\u00a0years who had clinical monitoring and a second skin biopsy after puberty to determine the disease course.<\/jats:p><\/jats:sec>Results<\/jats:title>Among cases of children to adolescents (<18\u00a0years), we observed a slight male predominance. Among children aged <14\u00a0years, sex ratio converged at 1:1. Early\u2010onset BN<\/jats:styled-content> showed a female predominance and hyperpigmented skin lesions. All BN<\/jats:styled-content> cases showed hyperpigmentation, and face and neck involvement tended to make severe cosmetic concerns. In contrast, hypertrichosis was more frequent in CSMH<\/jats:styled-content>. Either skin\u2010colored lesion or pseudo\u2010Darier's sign was not seen in early\u2010onset BN<\/jats:styled-content>. BN<\/jats:styled-content> showed less dermal smooth muscle than CSMH<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Androgens themselves do not seem to be related to the development of BN<\/jats:styled-content> but play only an aggravating role especially in male patients. Considering high occurrence in exposed areas, BN<\/jats:styled-content> may distress patients severely. As early laser treatment may be helpful in some patients with BN<\/jats:styled-content>, early\u2010onset BN<\/jats:styled-content> in comparison to CSMH<\/jats:styled-content> should be diagnosed appropriately.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13779","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T04:38:42Z","timestamp":1509511122000},"page":"55-61","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinicopathologic characteristics of early\u2010onset Becker's nevus in Korean children and adolescents"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9841-5797","authenticated-orcid":false,"given":"Young J.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi R.","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Gangnam Severance Hospital Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Gangnam Severance Hospital Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung I.","family":"Na","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seoul National University Bundang Hospital Gyeonggi\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3091-9256","authenticated-orcid":false,"given":"Joo Y.","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hanyang University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon M.","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung E.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,31]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1993.tb00041.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2012.01734.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.028"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.00988.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.scs.0000181049.99071.23"},{"key":"e_1_2_5_7_1","first-page":"1200","article-title":"Hypertrichotic skin\u2010colored patches in an infant. 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