{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:35:11Z","timestamp":1791848111477,"version":"4.3.4"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004685","name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004685","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Lichen planus pigmentosus (\n                    <jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>\n                    ) is considered a rare variant of lichen planus (\n                    <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                    ). It is characterized by acquired dark brown to gray macular pigmentation located on sun\u2010exposed areas of the face, neck, and flexures, commonly found in dark\u2010skinned patients. In patients with\n                    <jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>\n                    , an inflammatory lichenoid response results in marked pigmentary incontinence. It has been associated with hepatitis C virus, sun exposure, and contactants such as mustard oil and nickel.\n                    <jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>\n                    \u2010inversus affects fair and dark skin, predominantly involving flexural and intertriginous areas, while sun\u2010exposed areas are spared; friction is an associated trigger.\n                    <jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>\n                    along Blaschko's lines has been associated with susceptibility to genetic mosaicisms.\n                    <jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>\n                    can present concomitantly with other variants of\n                    <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\n                    such as frontal fibrosing alopecia, as well as endocrinopathies, and autoimmune diseases. Treatment is difficult and consists of avoidance of triggers and topical and systemic medications in order to stop the inflammatory reaction and reduce pigmentation, improving aesthetic appearance and quality of life.\n                  <\/jats:p>","DOI":"10.1111\/ijd.13806","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T23:40:45Z","timestamp":1509061245000},"page":"505-514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":125,"title":["Lichen planus pigmentosus and its variants: review and update"],"prefix":"10.1111","volume":"57","author":[{"given":"Juan Carlos","family":"Robles\u2010M\u00e9ndez","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Universitario \u201cDr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u201d Universidad Aut\u00f3noma de Nuevo Le\u00f3n Nuevo Le\u00f3n 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