{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:19:17Z","timestamp":1778869157311,"version":"3.51.4"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T00:00:00Z","timestamp":1513296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>The objective was to determine if the type and number of skin diseases can be clinical indicators of underlying immune status in HIV<\/jats:styled-content>1 disease by estimating and correlating with the CD<\/jats:styled-content>4 count and CDC<\/jats:styled-content> stage.<\/jats:p><\/jats:sec>Materials and methods<\/jats:title>This was a retrospective cross\u2010sectional descriptive study. All consecutive patients infected with HIV<\/jats:styled-content>1 followed at the Dermatology Department of Rabat Military Hospital between January 2008 and January 2017 were studied for dermatological manifestations, CD<\/jats:styled-content>4 count and CDC<\/jats:styled-content> clinical stage.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 170 patients with 304 dermatological manifestations were included. The most common dermatoses were fold dermatophytic infections (67%), genital warts (43%), herpes zoster (21%), xerosis (21%), and oral candidiasis (12%). The number of dermatologic manifestations was significantly greater in patients with CD<\/jats:styled-content>4 count less than 200\/mm3<\/jats:sup> or in stage C of the CDC<\/jats:styled-content> classification. Five types of skin diseases (dermatophyte infections of the folds, genital warts, shingles, oral candidiasis, and seborrheic dermatitis) were significantly associated (P<\/jats:italic> < 0.05) with CD<\/jats:styled-content>4 count <200\/mm3<\/jats:sup>. Seborrheic dermatitis was the only one skin disease significantly associated with AIDS<\/jats:styled-content> stage. In multivariate analysis, genital warts (OR = 0.3, 95% CI 0.10\u20130.92) are independently associated with CD<\/jats:styled-content>4 count less than 200 CD4\/mm3<\/jats:sup>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Skin manifestations not only act as markers but also reflect the underlying immune status. Seborrheic dermatitis and genital warts appear to be a marker of immune status, and seborrheic dermatitis appears to be associated with CDC<\/jats:styled-content> stage C, especially in their chronic and severe forms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13864","type":"journal-article","created":{"date-parts":[[2017,12,16]],"date-time":"2017-12-16T21:30:54Z","timestamp":1513459854000},"page":"156-161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Dermatologic manifestations among human immunodeficiency virus patients in Morocco and association with immune status"],"prefix":"10.1111","volume":"57","author":[{"given":"Hicham","family":"Titou","sequence":"first","affiliation":[{"name":"Dermatology Department Military Hospital Instruction Mohammed V University Mohammed V Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christelle","family":"Ebongo","sequence":"additional","affiliation":[{"name":"Dermatology Department Military Hospital Instruction Mohammed V University Mohammed V Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoufal","family":"Hjira","sequence":"additional","affiliation":[{"name":"Dermatology Department Military Hospital Instruction Mohammed V University Mohammed V Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,15]]},"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13864","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T03:19:09Z","timestamp":1695957549000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,15]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/ijd.13864"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13864","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,15]]},"assertion":[{"value":"2017-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-12-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}