{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:07:15Z","timestamp":1789556835152,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T00:00:00Z","timestamp":1517788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Actinomycetoma caused by Nocardia usually responds well to antibiotics. Emerging species of Nocardia, such as <jats:italic>N. wallacei<\/jats:italic>, can be a therapeutic challenge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>Confirm the therapeutic effectivity of linezolid in multidrug resistant <jats:italic>Nocardia Wallacei<\/jats:italic> actinomycetoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We evaluated the medical management of an 18\u2010year\u2010old man with multidrug resistant actinomycetoma of the left leg caused by <jats:italic>N. transvalensis<\/jats:italic> complex treated 17 years ago with linezolid 1200 mg a day. This bacteria was recently reclassified as <jats:italic>Nocardia Wallacei<\/jats:italic> by specific molecular biology technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The infection was cured after 3 months of treatment; the patient remained asymptomatic for the past 17 years. No adverse effects were found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Frequently, strains of <jats:italic>N. transvalensis<\/jats:italic> complex have aminoglycoside resistance; in this case, we highlight the effectiveness of linezolid for the successful medical management of multidrug resistant actinomycetoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Linezolid can be an alternative for the treatment of multidrug resistant <jats:italic>Nocardia Wallacei<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.13909","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T06:42:41Z","timestamp":1517812961000},"page":"580-582","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Disseminated actinomycetoma due to <i>Nocardia wallacei<\/i>"],"prefix":"10.1111","volume":"57","author":[{"given":"Oliverio","family":"Welsh","sequence":"first","affiliation":[{"name":"Universidad Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario Dr. Jose Gonzalez Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario C.","family":"Salinas\u2010Carmona","sequence":"additional","affiliation":[{"name":"Universidad Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario Dr. Jose Gonzalez Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara A.","family":"Brown\u2010Elliott","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Tyler Mycobacteria Nocardia Laboratory Tyler USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry","family":"Smith","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Tyler Mycobacteria Nocardia Laboratory Tyler USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus A.","family":"Cardenas\u2010De La Garza","sequence":"additional","affiliation":[{"name":"Universidad Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario Dr. Jose Gonzalez Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Richard J.","family":"Wallace","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Tyler Mycobacteria Nocardia Laboratory Tyler USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003218"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.31.11.2901-2906.1993"},{"key":"e_1_2_5_4_1","first-page":"18","article-title":"Identification of Nocardia species by partial sequencing of the 16S rRNA gene: the sun sets on Nocardia asteroides","volume":"68","author":"McNabb A","year":"2006","journal-title":"Can J Med Lab Sci"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00155-06"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02011-07"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2014.04.001"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2006.08.003"},{"key":"e_1_2_5_9_1","first-page":"586","article-title":"Update on the epidemiology of mycetoma in Mexico. 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