{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T22:01:44Z","timestamp":1789077704391,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Proven as effective acne scar treatment, ablative fractional carbon dioxide (<jats:styled-content style=\"fixed-case\">AFCO<\/jats:styled-content><jats:sub>2<\/jats:sub>) laser requires post\u2010laser wound healing care. <jats:styled-content style=\"fixed-case\">MAS<\/jats:styled-content>063<jats:styled-content style=\"fixed-case\">DP<\/jats:styled-content> is a multicomponent nonsteroidal anti\u2010inflammatory moisturizer for effective post\u2010laser treatment. This study compares the efficacy of <jats:styled-content style=\"fixed-case\">MAS<\/jats:styled-content>063<jats:styled-content style=\"fixed-case\">DP<\/jats:styled-content> and 0.02% triamcinolone acetonide (<jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>) lotion for post\u2010laser wound healing and complications. A split\u2010face, triple\u2010blinded, clinical study was performed in 16 patients, aged 20\u201350 years, receiving <jats:styled-content style=\"fixed-case\">AFCO<\/jats:styled-content><jats:sub>2<\/jats:sub> on both sides of the face, with <jats:styled-content style=\"fixed-case\">MAS<\/jats:styled-content>063<jats:styled-content style=\"fixed-case\">DP<\/jats:styled-content> on one side and 0.02% <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> on the other side for 7 days twice daily. Digital photography, hemoglobin, and melanin index at baseline were obtained immediately after laser treatment and then at days 3, 5, 7, and 30. Erythema, edema, crusting, adverse effects, and post\u2010inflammatory hyperpigmentation (<jats:styled-content style=\"fixed-case\">PIH<\/jats:styled-content>) were followed every visit. Sixteen patients, mean age 38.6 (8.4) years, with moderate\u2013severe atrophic scar and skin phototype <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> completed the study. Clinical improvement of edema, erythema, crusting, and hyperpigmentation was observed from day 3 to day 30 (<jats:italic>P<\/jats:italic> &lt; 0.001), with no statistically significant difference in both groups. There was also no statistical difference of hemoglobin, melanin index, and texture at days 3, 5, 7, and 30. Melanin index at day 30 was significantly less than baseline in both <jats:styled-content style=\"fixed-case\">MAS<\/jats:styled-content>063<jats:styled-content style=\"fixed-case\">DP<\/jats:styled-content> and 0.02% <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>. With <jats:styled-content style=\"fixed-case\">PIH<\/jats:styled-content> in 50% of cases, both treatments demonstrated good safety profiles and no serious adverse reactions. <jats:styled-content style=\"fixed-case\">MAS<\/jats:styled-content>063<jats:styled-content style=\"fixed-case\">DP<\/jats:styled-content> could be an effective treatment for post\u2010laser wound healing and complications, compatible to 0.02% <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/ijd.13922","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T10:20:36Z","timestamp":1518430836000},"page":"480-487","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Efficacy of <scp>MAS<\/scp>063<scp>DP<\/scp> lotion vs 0.02% triamcinolone acetonide lotion in improving post\u2010ablative fractional <scp>CO<\/scp><sub>2<\/sub> laser resurfacing wound healing: a split\u2010face, triple\u2010blinded, randomized, controlled trial"],"prefix":"10.1111","volume":"57","author":[{"given":"Suparuj","family":"Lueangarun","sequence":"first","affiliation":[{"name":"Division of Dermatology Chulabhorn International College of Medicine Thammasat University Amphur Klongluang Pathumthani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therdpong","family":"Tempark","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine Chulalongkorn University Pathumwan Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.08.051"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20659"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2010.01377.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22165"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22048"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1899"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.11.031"},{"key":"e_1_2_9_9_1","first-page":"236","article-title":"A multicenter, randomized, vehicle\u2010controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults","volume":"5","author":"Abramovits W","year":"2006","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2013.782090"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01803.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.014"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01434.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2009.08.009"},{"key":"e_1_2_9_15_1","first-page":"18","article-title":"Moist exposed therapy: an effective and valid alternative to occlusive dressings for postlaser resurfacing wound care","volume":"30","author":"Atiyeh BS","year":"2004","journal-title":"Dermatol Surg"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12332"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90690-8"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70082-7"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1517\/14656560902926106"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0083-6729(08)60447-1"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92633-S"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2003.09.046"},{"key":"e_1_2_9_23_1","first-page":"592","article-title":"Free radicals scavenging action and anti\u2010enzyme activities of procyanidines from Vitis vinifera. 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