{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:04:31Z","timestamp":1790946271251,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T00:00:00Z","timestamp":1518739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"Abstract<\/jats:title>Necrolytic migratory erythema (NME<\/jats:styled-content>) is a rare skin disorder that is a cutaneous manifestation of the glucagonoma syndrome. It presents with annular eruptions of migrating erythematous papules and plaques with superficial epidermal necrosis, central flaccid bullae, and crusted erosions located primarily in the intertriginous areas. Treatment with the long\u2010acting somatostatin analog Octreotide is a potential therapy to help ameliorate skin symptoms. We present a case of a patient with a 1\u2010year history of a pancreatic glucagonoma that developed an ulcerated, plaque\u2010like, weeping rash over multiple areas of their body despite current treatment with Octreotide and stable pancreatic tumor staging. The patient had a similar rash when initially diagnosed with a glucagonoma, and it quickly improved after Octreotide treatment. Clinical examination and biopsy were consistent with necrolytic migratory erythema due to an underlying glucagonoma. This rare case adds to our understanding of the clinical presentation of NME<\/jats:styled-content>, as well as highlights the relapsing and remitting course, even if the underlying pancreatic tumor is stable and the patient is undergoing treatment.<\/jats:p>","DOI":"10.1111\/ijd.13947","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T08:26:44Z","timestamp":1518769604000},"page":"642-645","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["A review of cutaneous manifestations within glucagonoma syndrome: necrolytic migratory erythema"],"prefix":"10.1111","volume":"57","author":[{"given":"Starling","family":"Tolliver","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline","family":"Graham","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin H.","family":"Kaffenberger","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,16]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04220.x"},{"key":"e_1_2_4_3_1","first-page":"e1","article-title":"Necrolytic migratory erythema: a common cutaneous clue of uncommon syndromes","volume":"92","author":"Stravropoulos P","year":"2013","journal-title":"Cutis"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012468409003"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1510531"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.01844.x"},{"key":"e_1_2_4_7_1","first-page":"40","article-title":"Necrolytic migratory erythema in an opiate\u2010dependent patient","volume":"33","author":"Muller FM","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2013.01.012"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1994.tb01792.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.04.030"},{"key":"e_1_2_4_11_1","first-page":"44","article-title":"Necrolytic migratory erythema with cryosurgery intervention","volume":"69","author":"Kamolwan P","year":"2017","journal-title":"Siriraj Med J"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i2.790"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.13947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.13947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T22:03:23Z","timestamp":1695506603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.13947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,16]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/ijd.13947"],"URL":"https:\/\/doi.org\/10.1111\/ijd.13947","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,16]]},"assertion":[{"value":"2017-06-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}