{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:51:21Z","timestamp":1778694681555,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,5,11]],"date-time":"2018-05-11T00:00:00Z","timestamp":1525996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Indian data on dermatitis herpetiformis (<jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>) is not available. The aim of this study was to investigate the demographic and clinicopathological characteristics of patients with <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content> and to study its association with other autoimmune diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All data were collected from case record forms of patients registered in immunobullous disease clinic of our institute. The diagnosis was based on characteristic clinical and immuno\/histopathological features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 65 patients were included, which constituted 9.47% of the registered patients in the immunobullous disease clinic over 3.5 years. The male to female ratio was 1.4 : 1; the average age was 44.35 \u00b1 15.52 years. Direct immunofluorescence showed granular IgA deposits at the papillary tips in 83.07% and basement membrane zone in 12.3% patients. Sixteen (24.1%) patients had associated celiac disease, and 15 (23.07%) patients had other autoimmune comorbidities such as hypothyroidism. Forty percent of patients on strict gluten\u2010free diet achieved remission in 2 years, while 35.4% had frequent relapses as they continued gluten intake.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dermatitis herpetiformis is not a rare disease in northern India as previously believed. The clinical, histological, and immunopathological characteristics of Indian <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content> patients are similar to those reported in Caucasian populations. The limitations of our study include an absence of genetic testing for <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">DQ<\/jats:styled-content>2 or <jats:styled-content style=\"fixed-case\">DQ<\/jats:styled-content>8, nonavailability of kits for detecting IgA specific for epidermal transglutaminase (IgA <jats:styled-content style=\"fixed-case\">eTG<\/jats:styled-content>), and short follow\u2010up period.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14029","type":"journal-article","created":{"date-parts":[[2018,5,12]],"date-time":"2018-05-12T04:15:50Z","timestamp":1526098550000},"page":"959-964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A retrospective study of dermatitis herpetiformis from an immunobullous disease clinic in north India"],"prefix":"10.1111","volume":"57","author":[{"given":"Sanjeev","family":"Handa","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology PGIMER Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garima","family":"Dabas","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology PGIMER Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipankar","family":"De","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology PGIMER Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology PGIMER Chandigarh 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