{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:03:09Z","timestamp":1769162589183,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T00:00:00Z","timestamp":1526601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Connective tissue autoimmune diseases (<jats:styled-content style=\"fixed-case\">CTAD<\/jats:styled-content>s) constitute a group of conditions, including rheumatoid arthritis; systemic lupus erythematosus; mixed connective tissue disease; calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia (<jats:styled-content style=\"fixed-case\">CREST<\/jats:styled-content>) syndrome; scleroderma; dermatomyositis; and Sj\u00f6gren syndrome. There are few studies on the alterations in filiform papillae in <jats:styled-content style=\"fixed-case\">CTAD<\/jats:styled-content>. Thus, the objective of this work was to determine whether there are changes in the macroscopic and dermoscopic patterns of filiform papillae.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This case\u2013control study included patients who were diagnosed with <jats:styled-content style=\"fixed-case\">CTAD<\/jats:styled-content>. The dependent variable was the dermoscopic pattern of filiform papillae of the tongue, and the independent variables were age, gender, time of evolution, and current treatment. A photograph of the back of the tongue was taken, and subsequently, the same site was examined by dermatoscopy. The microscopic and dermoscopic patterns of filiform papillae were classified (Maeda).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 50 cases and 50 controls, 94% of whom were female. The mean age was 43.96\u00a0\u00b1\u00a014.65\u00a0years. Of the cases with <jats:styled-content style=\"fixed-case\">CTAD<\/jats:styled-content>, 25% presented with a normal macroscopic pattern, versus 36% (18) with pattern <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>, 12% (6) with pattern <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, and 20% (10) with pattern <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>. The dermoscopic pattern was type I in 23 cases (46%), type <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> in 16 (32%), type <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> in 10 (20%), and type <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> in one patient (2%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We have noted alterations in filiform papillae in <jats:styled-content style=\"fixed-case\">CTAD<\/jats:styled-content>s, which emphasizes the importance of a detailed intraoral exploration and the macroscopic and dermoscopic evaluation of the dorsum of the tongue, specifically the filiform papillae.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14038","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T09:20:32Z","timestamp":1526635232000},"page":"938-942","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dermoscopic patterns of filiform papillae of the tongue in patients with and without connective tissue autoimmune diseases"],"prefix":"10.1111","volume":"57","author":[{"given":"Jos\u00e9 Manuel","family":"D\u00edaz\u2010Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Department of Dermatology National Institute of Medical Sciences and Nutrition \u201cDr. Salvador Zubir\u00e1n\u201d Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda E.","family":"Vega\u2010Memije","sequence":"additional","affiliation":[{"name":"Department of Dermatology General Hospital \u201cDr. Manuel Gea Gonz\u00e1lez\u201d Mexico City 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