{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:52:24Z","timestamp":1790275944276,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T00:00:00Z","timestamp":1528156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005297","name":"Uniwersytet Medyczny w Bialymstoku","doi-asserted-by":"publisher","award":["N\/ST\/ZB\/001\/1149"],"award-info":[{"award-number":["N\/ST\/ZB\/001\/1149"]}],"id":[{"id":"10.13039\/501100005297","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The average incidence of pemphigus reported from European countries ranged between 0.5 and eight cases per one million inhabitants. Studies on epidemiology of pemphigus group in entire Province of Poland over a period of more than a decade are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To analyze the incidence of pemphigus vulgaris (<jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content>) and pemphigus foliaceus (<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>) in Podlaskie Province (North\u2010East Poland) in years 2001\u20132015 with regard to patients\u2019 age, gender, and residency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010six cases of pemphigus were diagnosed in the period analyzed: 44 cases of <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> (66.67%) and 22 of <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> (33.33%). Female to male ratio was 2.88. The average incidence of <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> together was 3.67\u00a0\u00b1\u00a02.19 per one million inhabitants. In females the incidence was 5.34\u00a0\u00b1\u00a03.20 and in males, 1.90\u00a0\u00b1\u00a01.91 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The incidence in inhabitants of rural areas was 4.96\u00a0\u00b1\u00a04.07 and those of urban areas, 2.70\u00a0\u00b1\u00a02.01 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The age of the pemphigus onset was 54.69\u00a0\u00b1\u00a012.58 for <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and 64.24\u00a0\u00b1\u00a013.33 for <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The majority of <jats:styled-content style=\"fixed-case\">PV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> patients were residents of urban areas and rural areas, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence of pemphigus group in Podlaskie Province was within the range of the average incidence rates reported from other European countries. Surprisingly, the female to male ratio was the highest in Europe. Moreover, for the first time we have demonstrated that the incidence was higher in the population living in rural than in urban areas. Similar studies in other regions of Poland are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14078","type":"journal-article","created":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T01:25:35Z","timestamp":1528248335000},"page":"933-937","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Incidence of pemphigus vulgaris and pemphigus foliaceus in North\u2010East Poland (Podlaskie Province) \u2013 a 15\u2010year (2001\u20132015) bicentric retrospective study"],"prefix":"10.1111","volume":"57","author":[{"given":"Agnieszka B.","family":"Serwin","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Koper","sequence":"additional","affiliation":[{"name":"Diagnostic and Research Center for Sexually Transmitted Diseases Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwona","family":"Flisiak","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra061111"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-1811(99)00016-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2706"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00471.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.03010.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1998.00428.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00384.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04345.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00864.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02421.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.03044.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-014-1531-1"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02533.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09300.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12612836"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2008.06976_supp.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a180"},{"key":"e_1_2_7_19_1","first-page":"211","article-title":"The incidence of pemphigus in Lower Silesia","volume":"5","author":"Kolodziej T","year":"2003","journal-title":"Dermatol Klin"},{"key":"e_1_2_7_20_1","unstructured":"Chief Statistical Office.Statistical Yearbook of the Republic of Poland. 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