{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:20:09Z","timestamp":1758817209235,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T00:00:00Z","timestamp":1530748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous follicles that affects patients of all ages with a younger onset being more common than in the past.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate on the prevalence, clinical features and treatments of acne in 9 to 14\u2010year\u2010old patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational study was conducted between April 2016 and May 2016. The study population consisted of patients attending 32 different pediatric ambulatory clinics located in Italy (North: 56.25%, Center: 18.75%, South: 25%). For each patient, a specific questionnaire was registered: i) demographic data; ii) past personal history of acne; iii) auxologic parameters. Further data were gathered for patients suffering from acne at study enrollment: i) body areas involved by the disease; ii) acne severity evaluated through a 0\u20105 scale (Global Evaluation Acne scale); iii) acne treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 683 children (49.2% male; mean age 11.05 \u00b1 1.4 years) were enrolled. Acne was present in 234\/683 (34.3%) of the patients, and its prevalence increased with age being higher after 13 years of age (85\/234; 36.3%) and lowest at 9 years of age (14\/234; 6%). The majority of the patients suffering from acne showed a mild or almost clear disease state severity (<jats:styled-content style=\"fixed-case\">GEA<\/jats:styled-content> scale 1 or 2) (207\/234, 88.5%), whereas severe or very severe forms (<jats:styled-content style=\"fixed-case\">GEA<\/jats:styled-content> scale 4 or 5) represented only 4\/234, 1.7% of the cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Acne is not a rare disease in pre\u2010adolescent age. Adequate and prompt treatment is also needed in this class of patient to minimize disease burden and potential future disease worsening.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14138","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T11:29:04Z","timestamp":1530790144000},"page":"1320-1323","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Acne prevalence in 9 to 14\u2010year\u2010old old patients attending pediatric ambulatory clinics in Italy"],"prefix":"10.1111","volume":"57","author":[{"given":"Maddalena","family":"Napolitano","sequence":"first","affiliation":[{"name":"Department of Medicine and Health Science \u201cVincenzo Tiberio\u201d University of Molise Campobasso Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Family Pediatrician National Coordinator Dermatology Network 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