{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:55:51Z","timestamp":1783641351579,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T00:00:00Z","timestamp":1534896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Melioidosis is mainly observed in South\u2010East Asia, where <jats:italic>Burkholderia pseudomallei<\/jats:italic> is endemic. Cutaneous melioidosis (CM) has rarely been described and in contrast to systemic forms, there are no therapeutic recommendations to guide management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the literature published before January 2018, evaluating: dermatological presentation, natural history, diagnostic methods, and treatment options. We also distinguish between primary and secondary CM<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#ijd14167-bib-0001\"\/> in which the infection first started in the skin or came from an extracutaneous localization, respectively, and chronic CM<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#ijd14167-bib-0002\"\/> when duration exceeded 2 months. The recommended treatment for systemic forms included ceftazidime or meropenem, followed by oral maintenance therapy with cotrimoxazole or amoxicillin \u2013 clavulanic acid.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010three cases were published in 38 articles. Twenty\u2010nine patients (67.4%) were travelers, including 13 (44.8%) returning from Thailand. Thirty\u2010eight patients (88%) had primary CM, including nine (29.9%) with chronic infection. All cases of secondary CM first presented with acute infection. The median incubation time was 3 weeks. The most common presentation was cutaneous abscesses (58%). The recommended treatment was administered in 62.7% cases with 37.2% for maintenance therapy. Sixteen patients (37.2%) underwent surgery. Death was reported in less than 5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CM should be considered in travelers returning from or residents of endemic countries, particularly Thailand, presenting with cutaneous abscesses, cellulitis, or ulcerations. Surgery may be necessary in a substantial proportion of patients and follow\u2010up of at least 1 year is essential. Therapeutic recommendations need to be established.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14167","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T16:54:32Z","timestamp":1534956872000},"page":"221-227","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Cutaneous melioidosis: a review of the literature"],"prefix":"10.1111","volume":"58","author":[{"given":"Laura","family":"Fertitta","sequence":"first","affiliation":[{"name":"Infectious Diseases Department Sorbonne Universit\u00e9 Piti\u00e9 Salp\u00e9tri\u00e8re Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gentiane","family":"Monsel","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department Sorbonne Universit\u00e9 Piti\u00e9 Salp\u00e9tri\u00e8re Hospital Paris 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