{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:55:27Z","timestamp":1758477327764,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T00:00:00Z","timestamp":1537315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sentinel lymph node biopsy (<jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content>) is currently a routine procedure in the staging of patients with cutaneous melanoma; however, little information is available about the risk factors for postoperative complications, especially for the risk of seroma formation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of patients undergoing <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> at the University Hospital of Cologne, Germany, between 2011 and 2016, were reviewed. Binary logistic regression was used to analyze the influence of a wide range of variables on seroma development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 615 patients were included in the study. Overall, 20.4% of patients developed complications with seroma being the most common postoperative complication. Development of seroma was significantly more common among smokers than nonsmokers (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.956, <jats:italic>P<\/jats:italic> = 0.007). Inguinal localization (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 3.644, <jats:italic>P<\/jats:italic> &lt; 0.0001) was also associated with seroma formation. Male patients developed a seroma significantly more often than female patients following <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 2.104, <jats:italic>P<\/jats:italic> = 0.001). The presence or absence of metastasis in the lymph node did not influence seroma development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Male sex, inguinal localization, and smoking are risk factors for the development of seroma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14247","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T12:24:26Z","timestamp":1537359866000},"page":"185-189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Predicting risk for seroma development after axillary or inguinal sentinel lymph node biopsy in melanoma patients"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1469-4464","authenticated-orcid":false,"given":"Oana\u2010Diana","family":"Persa","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology University Hospital of Cologne Cologne 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