{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T07:40:13Z","timestamp":1784619613055,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T00:00:00Z","timestamp":1542844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Skin lesions are very common among organ transplant recipients (\n OTR<\/jats:styled-content>\n ), particularly infections and tumors, because of the immunosuppressive state these patients are put in.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n 177\n OTR<\/jats:styled-content>\n were examined. Skin lesions were categorized into neoplastic, infectious, and inflammatory diseases.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The mean age of\n OTR<\/jats:styled-content>\n was 52\u00a0years, the mean age at transplantation was 42.7\u00a0years, and kidney was the most common organ transplanted (72%). Skin lesions were found in 147 patients (83%). Cutaneous infections were seen in 106 patients (60%). Warts (30%) had the larger incidence and were associated with azathioprine (\n P<\/jats:italic>\n \u00a0=\u00a00.026), cyclosporine (\n P<\/jats:italic>\n \u00a0=\u00a00.006), and tacrolimus (\n P<\/jats:italic>\n \u00a0=\u00a00.009). Superficial mycoses occurred in 16% of\n OTR<\/jats:styled-content>\n , mostly onychomycosis, which was associated with tacrolimus (\n P<\/jats:italic>\n \u00a0=\u00a00.040). Actinic keratosis (\n AK<\/jats:styled-content>\n ) occurred in 31% of patients and cutaneous tumors in 56%. Squamous cell carcinoma (\n SCC<\/jats:styled-content>\n ) was the most common tumor type affecting 36% of\n OTR<\/jats:styled-content>\n (\n n<\/jats:italic>\n \u00a0=\u00a064), with invasive\n SCC<\/jats:styled-content>\n predominating over\n in\u00a0situ<\/jats:italic>\n SCC<\/jats:styled-content>\n , whereas basal cell carcinoma (\n BCC<\/jats:styled-content>\n ) accounted for 17%. Both\n SCC<\/jats:styled-content>\n and\n BCC<\/jats:styled-content>\n were more numerous in patients\u2019 skin type I (\n P<\/jats:italic>\n \u00a0<\u00a00.05).\n SCC<\/jats:styled-content>\n was more frequent (36%) in combined kidney and liver recipients (\n P<\/jats:italic>\n \u00a0=\u00a00.004), and\n BCC<\/jats:styled-content>\n was associated with cyclosporine (\n P<\/jats:italic>\n \u00a0=\u00a00.047). Inflammatory complications (acne, alopecia, hypertrichosis, and gingival overgrowth) were observed in 17.5% of patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Organ transplant recipients must be regularly evaluated by dermatologists, who should be alert to the onset of infections and skin (pre)malignant diseases in these patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijd.14285","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T10:15:36Z","timestamp":1545214536000},"page":"440-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Skin lesions in organ transplant recipients: a study of 177 consecutive Brazilian patients"],"prefix":"10.1111","volume":"58","author":[{"given":"Walmar R. P.","family":"Oliveira","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C. C. P.","family":"Tirico","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anaisa A. V.","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe R.","family":"Codarin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana L. C.","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyro","family":"Festa Neto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Cl\u00ednicas HCFMUSP Universidade de S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.06.067"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056364"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.55634"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07154.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09529.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)02743-3"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1316"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199003000-00006"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90154-3"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70157-2"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.062"},{"key":"e_1_2_5_13_1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4414\/smw.2009.12725","article-title":"Swiss clinical practice guidelines for skin cancer in organ transplant recipients","volume":"139","author":"Hofbauer GFL","year":"2009","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335152"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12320803"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-003-0100-6"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4425"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14537"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2003.tb00440.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.06.002"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20163954"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2012.08.010"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2012.10.004"},{"key":"e_1_2_5_24_1","first-page":"177","article-title":"Skin cancer in Caucasian renal allograft recipients living in a subtropical climate","volume":"87","author":"Hardie IR","year":"1980","journal-title":"Surgery"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199603150-00008"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1085-5629(03)00044-0"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb11841.x"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90239-2"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijd.14285","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.14285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T16:45:08Z","timestamp":1775321108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.14285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,22]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1111\/ijd.14285"],"URL":"https:\/\/doi.org\/10.1111\/ijd.14285","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,22]]},"assertion":[{"value":"2017-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}