{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T02:30:31Z","timestamp":1768271431112,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T00:00:00Z","timestamp":1550188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Skin and soft tissue infections (<jats:styled-content style=\"fixed-case\">SSTI<\/jats:styled-content>s) are a common cause of consultation, and complicated cases require hospitalization. We describe factors that are related to readmission and\/or mortality of hospitalized patients diagnosed with <jats:styled-content style=\"fixed-case\">SSTI<\/jats:styled-content>s.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of hospital\u2010admitted patients with a diagnosis of cellulitis, abscess, hidradenitis, fasciitis, and Fournier's gangrene. Cases from January 2002 to October 2015 were extracted from the diagnostic codification database of the Archives and Clinical Documentation Department.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>We studied 1,482 episodes of hospitalized patients diagnosed with <jats:styled-content style=\"fixed-case\">SSTI<\/jats:styled-content>s. There were 187 (12.3%) readmissions, the most frequent diagnosis was cellulitis (72.7%), and the most commonly isolated microorganism was <jats:italic>Staphylococcus aureus<\/jats:italic> (25; 30.1%). Factors associated with readmissions were healthcare\u2010related infections (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.002), prior antibiotic therapy (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), ischemic heart disease (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.01), chronic liver disease (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001), and diabetes mellitus (<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>) (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.006). The number of patients who died as a result of an infection was 34 (2.2%) and, in these patients, the most common diagnosis was also cellulitis (79.4%), which in 52.9% (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001) was community acquired. <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.01), heart failure (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001), and chronic liver disease (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003) were the most frequent comorbidities. This group presented more complications (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.005) such as endocarditis (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.005), amputation (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.018), severe sepsis (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.005), and septic shock (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Readmitted patients had healthcare\u2010related <jats:italic>S.\u00a0aureus<\/jats:italic> infection, had received prior antibiotic therapy, and presented comorbid conditions such as ischemic heart disease, peripheral vascular disease, chronic liver disease, or <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>. Comorbidities such as advanced age, <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>, heart failure, and chronic liver disease were associated with complications and higher infection\u2010related mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14390","type":"journal-article","created":{"date-parts":[[2019,2,16]],"date-time":"2019-02-16T04:43:17Z","timestamp":1550292197000},"page":"916-924","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Factors associated with readmission and mortality in adult patients with skin and soft tissue infections"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8669-3634","authenticated-orcid":false,"given":"Manuel","family":"Raya\u2010Cruz","sequence":"first","affiliation":[{"name":"Internal Medicine and Infectious Diseases Son Ll\u00e0tzer Hospital Balearic Islands 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