{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T18:44:15Z","timestamp":1751395455198},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Individuals infected with the human T\u2010cell lymphotropic virus type 1 (<jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101) commonly present skin lesions, which may be a warning sign for the diagnosis of infection. This study describes the most prevalent skin manifestations in <jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content> carriers attended at the clinic of N\u00facleo de Medicina Tropical (<jats:styled-content style=\"fixed-case\">NMT<\/jats:styled-content>) of the Universidade Federal do Par\u00e1 (<jats:styled-content style=\"fixed-case\">UFPA<\/jats:styled-content>) in Bel\u00e9m, Par\u00e1, Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a study of a series of cases of patients infected with human T\u2010cell lymphotropic virus types 1 and 2 (<jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101\/2) treated at <jats:styled-content style=\"fixed-case\">NMT UFPA<\/jats:styled-content> between 1999 and 2016. A descriptive analysis of data was applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 788 surveyed medical records in the service, 15.10% (<jats:italic>n<\/jats:italic> = 119) were referred to the dermatology clinic. From the series of cases that presented with skin lesions, 66.39% were female and 33.61% were male, and the average age of this group was 48 years. There was a predominance of patients with noninfectious inflammatory manifestations (64.2%), followed by infectious ones (24.6%), and 1.58% with lymphoproliferative diseases. As for the group of lesions, 45.26% of the erythematous\u2010squamous type were observed, followed by dyschromia (24.21%), and eczematous (14.74%). One patient with a diagnosis of adult T\u2010cell leukemia\/lymphoma, another with parapsoriasis, and four with infective dermatitis are highlighted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Skin disorders in the <jats:styled-content style=\"fixed-case\">HLTV<\/jats:styled-content> positive patient are important causes of referral to the dermatologist with etiological and skin lesions groups diversity. In the series of cases studied, lymphoproliferatives diseases and infective dermatitis associated with <jats:styled-content style=\"fixed-case\">HTLV<\/jats:styled-content>\u20101 were presented as a challenge for the diagnosis and clinical management of these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14422","type":"journal-article","created":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T01:27:44Z","timestamp":1553045264000},"page":"953-960","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dermatological manifestations in patients with human T\u2010cell lymphotropic virus at a reference service in Amazon"],"prefix":"10.1111","volume":"58","author":[{"given":"Brena","family":"Andrade de Sousa","sequence":"first","affiliation":[{"name":"Postgraduate Program in Parasitary Biology in the Amazon Center of Biological and Health Sciences State University of Par\u00e1 and Evandro Chagas Institute Bel\u00e9m, Par\u00e1 Brazil"},{"name":"Research Laboratory on Skin diseases of Sanitary Interest Center of Biological and Health Sciences State University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laisa V.","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Medicine course Center of Biological and Health Sciences State University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamires R.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Medicine course Center of Biological and Health Sciences State University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline L.","family":"Dias","sequence":"additional","affiliation":[{"name":"Medicine course Center of Biological and Health Sciences State University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Ara\u00fajo da Costa","sequence":"additional","affiliation":[{"name":"Research Laboratory in Tropical Dermatology and Endemic Diseases Nucleus of Tropical Medicine Federal University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita C.","family":"Medeiros Sousa","sequence":"additional","affiliation":[{"name":"Research Laboratory in Tropical Dermatology and Endemic Diseases Nucleus of Tropical Medicine Federal University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maisa S.","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular and Cellular Biology Nucleus of Tropical Medicine Federal University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00edlia B.","family":"Xavier","sequence":"additional","affiliation":[{"name":"Research Laboratory on Skin diseases of Sanitary Interest Center of Biological and Health Sciences State University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"},{"name":"Research Laboratory in Tropical Dermatology and Endemic Diseases Nucleus of Tropical Medicine Federal University of Par\u00e1 Bel\u00e9m, Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2012.06.007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0196-2013"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2011.12.006"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822009000300007"},{"key":"e_1_2_7_6_1","unstructured":"Brasil. 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